Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SQOR | Q9Y6N5 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775748 | 0.87 | SQOR (0.53) | ALDH1A1HPGDHSD17B10SQORKDM4E | |
| SCHEMBL15775763 | 0.83 | SQOR (0.49) | MEN1KMT2AALDH1A1MAPTSQOR | |
| SCHEMBL15775248 | 0.83 | PARP1 (0.47) | MAPTHPGDSQORKDM4EPARP1 | |
| SCHEMBL15775799 | 0.81 | SQOR (0.54) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL15775605 | 0.80 | NR1I3 (0.53) | SQORTACR3 | |
| SCHEMBL15775442 | 0.76 | SQOR (0.48) | MEN1KMT2AALDH1A1SQORADORA2A | |
| SCHEMBL15775546 | 0.76 | XDH (0.47) | ALDH1A1HPGDHSD17B10SQORKDM4E | |
| SCHEMBL15775195 | 0.76 | HSP90AA1 (0.47) | ALDH1A1CYP1A2CYP2C19GSK3AGSK3B | |
| SCHEMBL15775105 | 0.75 | SQOR (0.53) | ALDH1A1HPGDHSD17B10SQORKDM4E | |
| SCHEMBL15775484 | 0.74 | L3MBTL1 (0.48) | ALDH1A1HPGDHSD17B10SQORTACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |