Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | ACP1 | P24666 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | SQOR | Q9Y6N5 | 4/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775546 | 0.89 | XDH (0.47) | KDM4EIDO1SQORNPSR1HPGD | |
| SCHEMBL15775748 | 0.87 | SQOR (0.53) | PARP1ACP1KDM4EIDO1TDO2 | |
| SCHEMBL15775389 | 0.83 | ESR1 (0.45) | PARP1KDM4ESQORNPC1HPGD | |
| SCHEMBL15169766 | 0.82 | PARP1 (0.52) | PARP1ACP1KDM4EACHETOP1 | |
| SCHEMBL15775543 | 0.80 | LMNA (0.45) | ACP1KDM4EIDO1TDO2TNKS | |
| SCHEMBL15775763 | 0.80 | SQOR (0.49) | ACP1KDM4ESQORNPC1MAPT | |
| SCHEMBL15775490 | 0.79 | ACP1 (0.46) | ACP1KDM4ESQORACHETDP1 | |
| SCHEMBL15775799 | 0.77 | SQOR (0.54) | KDM4ESQORTOP1HPGDSMN1; SMN2 | |
| SCHEMBL15775605 | 0.76 | NR1I3 (0.53) | SQOR | |
| SCHEMBL15775442 | 0.73 | SQOR (0.48) | ACP1IDO1SQOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |