Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.58 |
| ▸ | RARB | P10826 | 6/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23236442 | 0.84 | OPRL1 (0.51) | OPRL1RARBOPRM1OPRD1OPRK1 | |
| SCHEMBL5452293 | 0.80 | FAAH (0.50) | OPRL1RARBOPRM1OPRD1OPRK1 | |
| SCHEMBL1581749 | 0.79 | OPRM1 (0.51) | OPRL1OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL1581964 | 0.78 | KMT2A (0.52) | ALDH1A1MEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL1581499 | 0.76 | MEN1 (0.58) | OPRL1OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL1581427 | 0.76 | OPRM1 (0.51) | OPRL1OPRM1OPRD1OPRK1DRD2 | |
| SCHEMBL15020023 | 0.76 | DRD2 (0.53) | RARBALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL1581919 | 0.76 | OPRM1 (0.56) | OPRL1OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL18910997 | 0.76 | OPRL1 (0.58) | OPRL1RARBOPRM1OPRD1OPRK1 | |
| SCHEMBL945210 | 0.75 | OPRL1 (0.69) | OPRL1OPRM1OPRD1OPRK1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720872-B1 | ARYL AND HETEROARYL-PIPERIDINECARBOXYLATE DERIVATIVES, THE PREPARATION AND THE USE THEREOF IN THE FORM OF FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2011-04-20 | — | — | EP | disclosed |