Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15840793 | 0.83 | HCAR3 (0.50) | HCAR3KDM4EALDH1A1POLBGAA | |
| SCHEMBL642243 | 0.78 | HCAR3 (0.53) | HCAR3KDM4EMYCALDH1A1HTT | |
| SCHEMBL1116007 | 0.77 | RXRA (0.50) | KDM4EALDH1A1LMNA | |
| SCHEMBL13191913 | 0.72 | KDM4E (0.48) | HCAR3KDM4EMYCHTTRAB9A | |
| SCHEMBL18677637 | 0.72 | ALDH1A1 (0.51) | KDM4EALDH1A1POLBGAAL3MBTL1 | |
| SCHEMBL6646574 | 0.71 | KMT2A (0.43) | HCAR3KDM4EMYCHTTPOLB | |
| SCHEMBL1884486 | 0.71 | HCAR3 (0.48) | HCAR3KDM4EALDH1A1POLBGAA | |
| Trimethylammonium SCHEMBL27801332 | 0.70 | KDM4E (0.60) | HCAR3KDM4EMYCALDH1A1RAB9A | |
| Trimethylammonium SCHEMBL27602719 | 0.70 | KDM4E (0.60) | HCAR3KDM4EMYCALDH1A1RAB9A | |
| SCHEMBL31401379 | 0.70 | ALDH1A1 (0.52) | HCAR3KDM4EMYCALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493352-B2 | Modular biocompatible materials for medical devices and uses thereof | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2016-11-15 | — | — | US | disclosed |
| US-20150118268-A1 | MODULAR BIOCOMPATIBLE MATERIALS FOR MEDICAL DEVICES AND USES THEREOF | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION | 2015-04-30 | — | — | US | disclosed |
| US-8771756-B2 | Biocompatible materials for medical devices | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2014-07-08 | — | — | US | disclosed |
| US-20140178504-A1 | MODULAR BIOCOMPATIBLE MATERIALS FOR MEDICAL DEVICES AND USES THEREOF | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150118268-A1 | MODULAR BIOCOMPATIBLE MATERIALS FOR MEDICAL DEVICES AND USES THEREOF | NOS3, NOS1, NOS2 | HCAR3 1389/4885KDM4E 2212/4885MYC 2099/4885 |
| US-20140178504-A1 | MODULAR BIOCOMPATIBLE MATERIALS FOR MEDICAL DEVICES AND USES THEREOF | NOS2, NOS3, NOS1 | HCAR3 1359/4885KDM4E 2901/4885MYC 3563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.