SCHEMBL158561

SCHEMBL158561

COC1=CC(=O)C(=O)C=C1C(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HKDC1 Q2TB90 2/20 0.43
ERBB2 P04626 1/20 0.41
IDO1 P14902 5/20 0.39
PTPN1 P18031 1/20 0.39
CDC25A P30304 1/20 0.39
CDC25B P30305 1/20 0.39
MAPT P10636 5/20 0.39
KMT2A Q03164 4/20 0.39
KDM4E B2RXH2 2/20 0.39
MEN1 O00255 2/20 0.39
TP53 P04637 2/20 0.39
CYP3A4 P08684 2/20 0.39
USP2 O75604 1/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ALDH1A1 P00352 3/20 0.39
ATM Q13315 3/20 0.39
HPGD P15428 2/20 0.39
CES2 O00748 1/20 0.39
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3417111 0.77 HKDC1 (0.56) HKDC1ERBB2IDO1PTPN1CDC25A
SCHEMBL4062188 0.73 HKDC1 (0.31) HKDC1IDO1
SCHEMBL49783 0.72 MAPT (0.50) HKDC1MAPTKMT2AMEN1MAPK1
SCHEMBL49737 0.72 ERBB2 (0.62) HKDC1ERBB2IDO1PTPN1CDC25A
SCHEMBL5920181 0.71 MAPT (0.34) HKDC1ERBB2MAPTKMT2AKDM4E
SCHEMBL28856262 0.69 ERBB2 (0.59) HKDC1ERBB2IDO1PTPN1CDC25A
SCHEMBL11025815 0.69 MAPT (0.50) HKDC1ERBB2IDO1PTPN1CDC25A
SCHEMBL15759639 0.68 MAPT (0.50) HKDC1ERBB2IDO1PTPN1CDC25A
SCHEMBL9275509 0.67 HKDC1 (0.46) HKDC1ERBB2IDO1PTPN1CDC25A
SCHEMBL20201393 0.67 MAPT (0.41) MAPTKMT2AALDH1A1ATMHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 566 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119912606-A Catalyst suitable for ethylene polymerization reaction and preparation method and application thereof 中国石油化工股份有限公司 2025-05-02 CN claimed
CN-118993854-A Rare earth promoted lignin beta-O-4 model compound oxidation method 浙江大学衢州研究院 2024-11-22 CN claimed
US-20220304944-A1 METHODS FOR REDUCING THC CONTENT IN COMPLEX CANNABINOID MIXTURES IN WHICH THC IS A MINOR COMPONENT CANOPY GROWTH CORPORATION (CA) 2022-09-29 US claimed
EP-2603598-B1 COMPOSITIONS COMPRISING A GH61 POLYPEPTIDE HAVING CELLULOLYTIC ENHANCING ACTIVITY AND A QUINONE COMPOUND AND USES THEREOF NOVOZYMES INC (US) 2018-04-18 EP claimed
US-20180019412-A1 Compositions Comprising A Polypeptide Having Cellulolytic Enhancing Activity And A Quinone Compound And Uses Thereof NOVOZYMES, INC. (US) 2018-01-18 US claimed
US-9752168-B2 Compositions comprising a polypeptide having cellulolytic enhancing activity and a quinone compound and uses thereof NOVOZYMES, INC. (US) 2017-09-05 US claimed
US-9663804-B2 Method of treating polyester textile NOVOZYMES A/S (DK) 2017-05-30 US claimed
US-20160251686-A1 Compositions Comprising A Polypeptide Having Cellulolytic Enhancing Activity And A Quinone Compound And Uses Thereof NOVOZYMES INC (US) 2016-09-01 US claimed
US-9273335-B2 Compositions comprising a polypeptide having cellulolytic enhancing activity and a quinone compound and uses thereof NOVOZYMES, INC. (US) 2016-03-01 US claimed
US-20130164791-A1 Compositions Comprising A Polypeptide Having Cellulolytic Enhancing Activity And A Quinone Compound And Uses Thereof NOVOZYMES, INC. (US) 2013-06-27 US claimed
EP-2603598-A1 COMPOSITIONS COMPRISING A POLYPEPTIDE HAVING CELLULOLYTIC ENHANCING ACTIVITY AND A QUINONE COMPOUND AND USES THEREOF Novozymes, Inc. (US) 2013-06-19 EP claimed
WO-2012021394-A1 COMPOSITIONS COMPRISING A POLYPEPTIDE HAVING CELLULOLYTIC ENHANCING ACTIVITY AND A QUINONE COMPOUND AND USES THEREOF NOVOZYMES, INC. (US) 2012-02-16 WO claimed
US-12600996-B2 Carbohydrate binding module variants and hybrid polypeptides comprising same NOVOZYMES A/S (DK) 2026-04-14 US disclosed
CN-119912606-A Catalyst suitable for ethylene polymerization reaction and preparation method and application thereof 中国石油化工股份有限公司 2025-05-02 CN disclosed
US-20250092434-A1 CELLULOLYTIC ENZYME COMPOSITIONS AND USES THEREOF NOVOZYMES, INC. (US) 2025-03-20 US disclosed
US-12195776-B2 Cellulolytic enzyme compositions and uses thereof NOVOZYMES, INC. (US) 2025-01-14 US disclosed
US-20100129723-A1 NON-AQUEOUS ELECTROLYTE FOR PRIMARY BATTERY, AND NON-AQUEOUS ELECTROLYTE PRIMARY BATTERY USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2010-05-27 US disclosed
EP-1933404-A1 NON-AQUEOUS ELECTROLYTE FOR PRIMARY BATTERY, AND NON-AQUEOUS ELECTROLYTE PRIMARY BATTERY USING THE SAME Mitsubishi Chemical Corporation (JP) 2008-06-18 EP disclosed
US-7241551-B2 Positive-working resist composition FUJIFILM CORPORATION (JP) 2007-07-10 US disclosed
US-7241551-B2 Positive-working resist composition FUJIFILM CORPORATION (JP) 2007-07-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600996-B2 Carbohydrate binding module variants and hybrid polypeptides comprising same QPCTL, DNTT, RNGTT HKDC1 1589/4885ERBB2 4833/4885IDO1 3267/4885
US-20180019412-A1 Compositions Comprising A Polypeptide Having Cellulolytic Enhancing Activity And A Quinone Compound And Uses Thereof PGLS, CEL, PNLIP HKDC1 1376/4885ERBB2 4571/4885IDO1 1922/4885
US-20220304944-A1 METHODS FOR REDUCING THC CONTENT IN COMPLEX CANNABINOID MIXTURES IN WHICH THC IS A MINOR COMPONENT CNR2, CNR1, FAAH HKDC1 3546/4885ERBB2 586/4885IDO1 1192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.