Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15870258 | 0.85 | — | — | |
| SCHEMBL15870253 | 0.83 | — | — | |
| SCHEMBL6980920 | 0.77 | ADRA2A (0.55) | MTNR1A | |
| SCHEMBL7200942 | 0.76 | MTNR1A (1.00) | MTNR1A | |
| SCHEMBL15870213 | 0.76 | HTR1A (0.52) | — | |
| SCHEMBL17272716 | 0.76 | HTR1A (0.52) | — | |
| SCHEMBL8381361 | 0.76 | ADRA2C (0.48) | MTNR1A | |
| SCHEMBL6980987 | 0.76 | ADRA2C (0.48) | MTNR1A | |
| SCHEMBL11107814 | 0.76 | DRD2 (0.56) | MTNR1A | |
| SCHEMBL17272739 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014106660-A1 | NOVEL BENZODIOXANE-PIPERIDINE DERIVATIVES AND THERAPEUTIC USES THEREOF FOR THE TREATMENT OF NEUROPSYCHIATRIC DISORDERS | PIERRE FABRE MEDICAMENT (FR) | 2014-07-10 | — | — | WO | disclosed |