Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31513861 | 0.96 | — | — | |
| Iodide SCHEMBL5088138 | 0.92 | TSHR (0.35) | TSHRDNM1OPRM1THRBSPHK1 | |
| Bromide SCHEMBL5087073 | 0.92 | DNM1 (0.40) | TSHRDNM1OPRM1THRBSPHK1 | |
| Hydrochloric Acid SCHEMBL5087095 | 0.92 | TSHR (0.35) | TSHRDNM1OPRM1THRBSPHK1 | |
| Water SCHEMBL31683014 | 0.85 | — | — | |
| SCHEMBL29624055 | 0.80 | — | — | |
| SCHEMBL31745087 | 0.79 | DNM1 (0.55) | TSHRDNM1OPRM1THRBSPHK1 | |
| Water SCHEMBL11520091 | 0.77 | DNM1 (0.53) | TSHRDNM1OPRM1THRBSPHK1 | |
| Hydrochloric Acid SCHEMBL31683069 | 0.77 | — | — | |
| Bromide SCHEMBL31683056 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12012658-B2 | Composition, kit, and method for treating substrate | FUJIFILM CORPORATION (JP) | 2024-06-18 | — | — | US | disclosed |
| US-20220119960-A1 | COMPOSITION, KIT, AND METHOD FOR TREATING SUBSTRATE | FUJIFILM CORPORATION (JP) | 2022-04-21 | — | — | US | disclosed |
| WO-2021005980-A1 | COMPOSITION, KIT, AND TREATMENT METHOD FOR SUBSTRATE | 富士フイルム株式会社 | 2021-01-14 | — | — | WO | disclosed |
| US-9944853-B2 | Color inhibitor for quaternary ammonium hydroxide in non-aqueous solvent | SACHEM, INC. (US) | 2018-04-17 | — | — | US | disclosed |
| EP-2943465-B1 | COLOR INHIBITOR FOR QUATERNARY AMMONIUM HYDROXIDE IN NON-AQUEOUS SOLVENT | SACHEM INC (US) | 2017-03-15 | — | — | EP | disclosed |
| US-20150353824-A1 | COLOR INHIBITOR FOR QUATERNARY AMMONIUM HYDROXIDE IN NON-AQUEOUS SOLVENT | SACHEM, INC. | 2015-12-10 | — | — | US | disclosed |
| EP-2943465-A1 | COLOR INHIBITOR FOR QUATERNARY AMMONIUM HYDROXIDE IN NON-AQUEOUS SOLVENT | Sachem, Inc. (US) | 2015-11-18 | — | — | EP | disclosed |
| CN-104936943-A | COLOR INHIBITOR FOR QUATERNARY AMMONIUM HYDROXIDE IN NON-AQUEOUS SOLVENT | SACHEM INC | 2015-09-23 | — | — | CN | disclosed |
| WO-2014110308-A1 | COLOR INHIBITOR FOR QUATERNARY AMMONIUM HYDROXIDE IN NON-AQUEOUS SOLVENT | SACHEM, INC. (US) | 2014-07-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353824-A1 | COLOR INHIBITOR FOR QUATERNARY AMMONIUM HYDROXIDE IN NON-AQUEOUS SOLVENT | IDH3A, IDH3B, DHX35 | TSHR 4118/4885DNM1 185/4885OPRM1 2282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.