Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3775207 | 0.95 | RAB9A (0.63) | RAB9AKMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL483578 | 0.89 | RAB9A (0.74) | RAB9AKMT2ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL2840152 | 0.86 | SMN1; SMN2 (0.56) | RAB9ASMN1; SMN2CYP1A2CYP2C19NPC1 | |
| SCHEMBL2846951 | 0.85 | SMN1; SMN2 (0.55) | RAB9ASMN1; SMN2CYP1A2CYP2C19NPC1 | |
| SCHEMBL2843465 | 0.81 | SMN1; SMN2 (0.58) | RAB9ASMN1; SMN2CYP1A2CYP2C19NPC1 | |
| SCHEMBL1394203 | 0.81 | RAB9A (0.74) | RAB9AKMT2ASMN1; SMN2NPC1LMNA | |
| SCHEMBL10542399 | 0.81 | LMNA (0.54) | RAB9ASMN1; SMN2CYP1A2CYP2C19LMNA | |
| SCHEMBL8779817 | 0.80 | HDAC1 (0.79) | RAB9ASMN1; SMN2NPC1LMNAPOLB | |
| SCHEMBL5259033 | 0.80 | NAMPT (0.49) | RAB9AKMT2ASMN1; SMN2NPC1LMNA | |
| SCHEMBL166484 | 0.80 | LMNA (0.82) | RAB9AKMT2ASMN1; SMN2CYP1A2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092558-A1 | NOVEL MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-21 | — | — | US | disclosed |
| EP-2262776-A2 | NOVEL MICROBIOCIDES | Syngenta Participations AG (CH) | 2010-12-22 | — | — | EP | disclosed |
| US-20090318290-A1 | N-(4-PYRIDIN-2-YLBUTYL) BENZAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2009-12-24 | — | — | US | disclosed |
| WO-2009127722-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-10-22 | — | — | WO | disclosed |
| WO-2009127718-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-10-22 | — | — | WO | disclosed |
| WO-2009127726-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-10-22 | — | — | WO | disclosed |
| EP-2041090-A1 | N- (4-PYRIDIN-2-YLBUTYL) BENZAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | Bayer CropScience SA (FR) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008003745-A1 | N- (4-PYRIDIN-2-YLBUTYL) BENZAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2008-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092558-A1 | NOVEL MICROBIOCIDES | FPR1, CD14, MPO | RAB9A 1548/4885KMT2A 4219/4885SMN1; SMN2 4007/4885 |
| US-20090318290-A1 | N-(4-PYRIDIN-2-YLBUTYL) BENZAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | CYP1A2, CYP51A1, CYP4B1 | RAB9A 2823/4885KMT2A 1185/4885SMN1; SMN2 1992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.