Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.36 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.34 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15356747 | 0.84 | POLQ (0.40) | CYP2A6PRMT5TGFBR1NOTUMRIPK2 | |
| SCHEMBL2732597 | 0.81 | CYP2A6 (0.42) | CYP2A6PRMT5TGFBR1RIPK2ERCC5 | |
| SCHEMBL4965578 | 0.81 | CYP2A6 (0.42) | CYP2A6PRMT5TGFBR1RIPK2ERCC5 | |
| SCHEMBL2690115 | 0.81 | CYP2A6 (0.39) | CYP2A6PRMT5TGFBR1RIPK2ERCC5 | |
| SCHEMBL15975571 | 0.81 | ALDH1A1 (0.38) | CYP2A6PRMT5TGFBR1NOTUMRIPK2 | |
| SCHEMBL15975572 | 0.78 | CYP2A6 (0.39) | CYP2A6PRMT5TGFBR1RIPK2ERCC5 | |
| SCHEMBL14904631 | 0.78 | MLYCD (0.50) | CYP2A6RIPK2ALDH1A1NPC1RAB9A | |
| SCHEMBL14904608 | 0.77 | LMNA (0.37) | CYP2A6PRMT5TGFBR1RIPK2ERCC5 | |
| SCHEMBL2690352 | 0.75 | GPR119 (0.42) | CYP2A6PRMT5TGFBR1RIPK2ERCC5 | |
| SCHEMBL2730846 | 0.74 | HTT (0.48) | CYP2A6PRMT5TGFBR1RIPK2ERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140213448-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2014-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213448-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | CYP2A6 368/4885PRMT5 1049/4885TGFBR1 1799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.