Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
| ▸ | DRD4 | P21917 | 4/20 | 0.58 |
| ▸ | DRD2 | P14416 | 7/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 4/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.55 |
| ▸ | DHFR | P00374 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15938001 | 0.90 | DRD4 (0.60) | HTR7ALDH1A1KDM4EMAPTDRD4 | |
| SCHEMBL7498974 | 0.89 | DRD4 (0.72) | HTR7DRD4DRD2DRD3HTR1A | |
| SCHEMBL15937926 | 0.88 | MAPT (0.61) | HTR7ALDH1A1KDM4EMAPTDRD4 | |
| SCHEMBL6858091 | 0.87 | ALDH1A1 (0.76) | HTR7ALDH1A1KDM4EMAPTKCNH2 | |
| SCHEMBL10568088 | 0.85 | LMNA (0.62) | HTR7ALDH1A1KDM4EMAPTKCNH2 | |
| SCHEMBL15938394 | 0.84 | MAPT (0.71) | ALDH1A1KDM4EMAPTKCNH2DRD4 | |
| SCHEMBL15938111 | 0.84 | DRD2 (0.63) | ALDH1A1DRD4DRD2DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL10574116 | 0.84 | LMNA (0.60) | HTR7ALDH1A1KDM4EMAPTKCNH2 | |
| SCHEMBL15937714 | 0.84 | SIGMAR1 (0.66) | HTR7ALDH1A1MAPTKCNH2DRD4 | |
| SCHEMBL15937785 | 0.82 | DRD4 (0.62) | HTR7DRD4DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883796-B2 | Biphenyl derivatives, pharmaceutical composition comprising the same, and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-11-11 | — | — | US | disclosed |
| US-20140228568-A1 | BIPHENYL DERIVATIVES, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140228568-A1 | BIPHENYL DERIVATIVES, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND PREPARATION METHOD THEREOF | HTR7, HTR6, HTR3B | HTR7 1/4885ALDH1A1 917/4885KDM4E 3428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.