SCHEMBL15944446

SCHEMBL15944446

Cc1ccc(SSc2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 1/20 0.55
FBP1 P09467 2/20 0.49
BCHE P06276 1/20 0.45
ACHE P22303 1/20 0.45
TSHR P16473 2/20 0.42
CYP1A1 P04798 1/20 0.42
CYP1B1 Q16678 1/20 0.42
ALDH1A1 P00352 2/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA5A P35218 1/20 0.41
CA9 Q16790 1/20 0.41
KIF11 P52732 3/20 0.40
NFE2L2 Q16236 1/20 0.39
HAO1 Q9UJM8 1/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 1/20 0.38
EPHX2 P34913 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL944341 0.88 FBP1 (0.57) FBP1TSHRALDH1A1KIF11HAO1
SCHEMBL506624 0.86 MLYCD (0.66) MLYCDBCHEACHETSHRCYP1A1
SCHEMBL91414 0.85 TSHR (0.55) MLYCDBCHEACHETSHRCYP1A1
SCHEMBL17816159 0.85 TSHR (0.55) MLYCDBCHEACHETSHRCYP1A1
Ammonia Solution, Strong SCHEMBL28559843 0.83 TSHR (0.52) MLYCDBCHEACHETSHRCYP1A1
Bromide SCHEMBL27849066 0.83 TSHR (0.52) MLYCDBCHEACHETSHRCYP1A1
SCHEMBL57311 0.80 ACHE (0.57) MLYCDFBP1ACHETSHRALDH1A1
SCHEMBL13019482 0.78 KIF11 (0.61) BCHEACHETSHRCYP1A1CYP1B1
SCHEMBL17110032 0.78 KIF11 (0.61) BCHEACHETSHRCYP1A1CYP1B1
SCHEMBL1044865 0.78 KIF11 (0.61) BCHEACHETSHRCYP1A1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9414588-B2 Herbicide composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-16 US disclosed
US-20150289505-A1 HERBICIDE COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-9101140-B2 Cyclohexanone compounds and herbicides comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-08-11 US disclosed
US-20140228219-A1 CYCLOHEXANONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140228219-A1 CYCLOHEXANONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME CBR3, CBR1, CYP2S1 MLYCD 691/4885FBP1 2144/4885BCHE 409/4885
US-20150289505-A1 HERBICIDE COMPOSITION DDT, DHFR, DERL1 MLYCD 1243/4885FBP1 1251/4885BCHE 928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.