SCHEMBL944341

SCHEMBL944341

FC(F)(F)c1ccc(SSc2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.57
ALDH1A1 P00352 1/20 0.48
TSHR P16473 1/20 0.48
KIF11 P52732 6/20 0.46
EPHX2 P34913 1/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
ORAI1 Q96D31 1/20 0.44
ORAI2 Q96SN7 1/20 0.44
ORAI3 Q9BRQ5 1/20 0.44
TRPV6 Q9H1D0 1/20 0.44
MGLL Q99685 1/20 0.44
HAO1 Q9UJM8 1/20 0.44
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15944446 0.88 MLYCD (0.55) FBP1ALDH1A1TSHRKIF11EPHX2
SCHEMBL946860 0.86 FBP1 (0.47) FBP1ALDH1A1TSHRKIF11
SCHEMBL21323258 0.85 FBP1 (0.46) FBP1ALDH1A1TSHRKIF11CES2
SCHEMBL2417142 0.82 HAO1 (0.53) FBP1ALDH1A1TSHRKIF11CES2
SCHEMBL63468 0.80 ALDH1A1 (0.67) ALDH1A1TSHRKIF11EPHX2CES2
SCHEMBL19996403 0.80 CES2 (0.48) FBP1ALDH1A1TSHRKIF11EPHX2
Fluoride SCHEMBL29094698 0.80 HAO1 (0.52) FBP1ALDH1A1TSHRKIF11CES2
SCHEMBL23182981 0.78 ALDH1A1 (0.43) FBP1ALDH1A1TSHRKIF11EPHX2
SCHEMBL695441 0.78 ALDH1A1 (0.43) FBP1ALDH1A1TSHRKIF11CES2
SCHEMBL20072348 0.78 ALDH1A1 (0.43) FBP1ALDH1A1TSHRKIF11EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120004826-A Method for preparing organic thioether compound by utilizing photocatalysis 南京工业大学 2025-05-16 CN disclosed
CN-116283684-B Green preparation method of diphenyl sulfide and derivative thereof 常州大学 2025-04-08 CN disclosed
CN-116283684-A Green preparation method of diphenyl sulfide and derivative thereof 常州大学 2023-06-23 CN disclosed
CN-113387855-B Method for synthesizing disulfide compound by visible light and titanocene complex concerted catalysis 陕西师范大学 2023-04-14 CN disclosed
WO-2023001999-A1 C2-THIOETHER TRYPTOPHAN TRIMERS AND TETRAMERS FOR THE TREATMENT OF BETACORONOAVIRUS INFECTIONS 1. CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) 2023-01-26 WO disclosed
US-20220119351-A1 SPIROPIPERIDINE ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS MERCK SHARP & DOHME CORP. (US) 2022-04-21 US disclosed
US-11185742-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2021-11-30 US disclosed
CN-113387855-A Method for synthesizing disulfide compound by using visible light and titanocene complex under concerted catalysis 陕西师范大学 2021-09-14 CN disclosed
EP-3677318-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2021-05-05 EP disclosed
WO-2020223136-A1 SPIROPIPERIDINE ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS MERCK SHARP & DOHME CORP. (US) 2020-11-05 WO disclosed
EP-1395590-A2 DIHYDROPYRROLO[1,2-A]INDOLE AND TETRAHYDROPYRIDO[1,2-A]INDOLE DERIVATIVES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS Merck Frosst Canada & Co. (CA) 2004-03-10 EP disclosed
WO-2004014825-A1 CANNABINOID RECEPTOR LIGANDS SCHERING CORPORATION (US) 2004-02-19 WO disclosed
US-20030232859-A1 Cannabinoid receptor ligands SCHERING CORPORATION 2003-12-18 US disclosed
EP-1368308-A1 CANNABINOID RECEPTOR LIGANDS Schering Corporation (US) 2003-12-10 EP disclosed
WO-2002062750-A9 CANNABINOID RECEPTOR LIGANDS SCHERING CORP (US) 2003-09-18 WO disclosed
US-20030096844-A1 Sulfonamide-containing benzene derivatives which exhibit anti-inflammatory and immunodulatory activity SCHERING CORPORATION 2003-05-22 US disclosed
WO-2002094830-A2 DIHYDROPYRROLO[1,2-A]INDOLE AND TETRAHYDROPYRIDO[1,2-a]-INDOLE DERIVATIVES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS MERCK FROSST CANADA & CO. (CA) 2002-11-28 WO disclosed
US-20020122988-A1 Efficiency UBE INDUSTRIES, LTD. (JP) 2002-09-05 US disclosed
WO-2002062750-A1 CANNABINOID RECEPTOR LIGANDS SCHERING CORPORATION (US) 2002-08-15 WO disclosed
EP-1199766-A2 Non-aqueous secondary battery having enhanced discharge capacity retention Ube Industries, Ltd. (JP) 2002-04-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030096844-A1 Sulfonamide-containing benzene derivatives which exhibit anti-inflammatory and immunodulatory activity SULT2A1, NFKBIA, SULT1A1 FBP1 152/4885ALDH1A1 85/4885TSHR 4605/4885
US-20220119351-A1 SPIROPIPERIDINE ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS CHRNA7, CHRNA5, CHRNA2 FBP1 2845/4885ALDH1A1 1011/4885TSHR 468/4885
US-20030232859-A1 Cannabinoid receptor ligands CNR1, CNR2, GPR18 FBP1 1111/4885ALDH1A1 1021/4885TSHR 1432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.