SCHEMBL15949869

SCHEMBL15949869

C[Si](C)O[Si](C)(C)Cc1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
ALDH1A1 P00352 2/20 0.37
TP53 P04637 1/20 0.36
AOC3 Q16853 2/20 0.34
TAAR1 Q96RJ0 1/20 0.34
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34
CALM1 P0DP23 1/20 0.33
LTA4H P09960 1/20 0.32
IDO1 P14902 2/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5388447 0.78 TSHR (0.42) TSHRALDH1A1TP53AOC3TAAR1
SCHEMBL109029 0.76 TSHR (0.41) TSHRALDH1A1TP53AOC3TAAR1
SCHEMBL14665751 0.74 TSHR (0.39) TSHRALDH1A1TP53AOC3TAAR1
SCHEMBL243501 0.74 TSHR (0.39) TSHRALDH1A1TP53AOC3TAAR1
SCHEMBL13550868 0.74 TSHR (0.39) TSHRALDH1A1TP53AOC3TAAR1
SCHEMBL109170 0.72 TP53 (0.42) TSHRALDH1A1TP53AOC3TAAR1
SCHEMBL534142 0.71 TSHR (0.41) TSHRALDH1A1TP53AOC3TAAR1
SCHEMBL8320761 0.71 TP53 (0.41) TSHRALDH1A1TP53AOC3TAAR1
SCHEMBL15949871 0.71 ALDH1A1 (0.41) TSHRALDH1A1TP53AOC3TAAR1
SCHEMBL16459782 0.69 TSHR (0.35) TSHRALDH1A1TP53AOC3TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2767571-B1 FLUORESCENT COMPOUND, METHOD FOR PRODUCING THE SAME, AND FLUORESCENT RESIN COMPOSITION SHINETSU CHEMICAL CO (JP) 2016-12-21 EP disclosed
US-9217071-B2 Fluorescent compound, method for producing the same, and fluorescent resin composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-12-22 US disclosed
US-20140235774-A1 FLUORESCENT COMPOUND, METHOD FOR PRODUCING THE SAME, AND FLUORESCENT RESIN COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-08-21 US disclosed
EP-2767571-A1 Fluorescent compound, method for producing the same, and fluorescent resin composition Shin-Etsu Chemical Co., Ltd. (JP) 2014-08-20 EP disclosed