SCHEMBL15960959

SCHEMBL15960959

Cc1ccc(Nc2ccc(C(C)c3ccncc3)c3ccccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT1 P17948 1/20 0.44
KDR P35968 1/20 0.44
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
ADRA2A P08913 2/20 0.40
KDM1A O60341 1/20 0.38
GAA P10253 3/20 0.38
MAPT P10636 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
ADRA1A P35348 1/20 0.38
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
HPGD P15428 1/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15960969 0.89 HPGD (0.44) KDM4EALDH1A1KDM1AGAAMAPT
SCHEMBL15960960 0.84 MMP2 (0.40) KDM4EKDM1AGAAMAPTTDP1
SCHEMBL15960962 0.82 RAB9A (0.50) KDM4EALDH1A1KDM1AGAAMAPT
SCHEMBL15960971 0.81 CYP2A6 (0.39) KDM4EKDM1AGAAMAPTTDP1
SCHEMBL15960963 0.80 GAA (0.36) KDM4EKDM1AGAAMAPTTDP1
SCHEMBL15960964 0.78 HPGD (0.45) KDM4EALDH1A1ADRA2AKDM1AGAA
SCHEMBL15960968 0.76 CDC25B (0.42) KDM4EALDH1A1KDM1AGAAMAPT
SCHEMBL21165374 0.76 HPGD (0.46) KDM4EALDH1A1KDM1AGAAMAPT
SCHEMBL15960961 0.74 RAB9A (0.38) KDM4EALDH1A1KDM1AGAAMAPT
SCHEMBL21165373 0.71 HPGD (0.37) KDM4EALDH1A1KDM1AGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230333474-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION COMPRISING FLUOROALKYL GROUP-CONTAINING ORGANIC ACID OR SALT THEREOF NISSAN CHEMICAL CORPORATION (JP) 2023-10-19 US disclosed
US-9263286-B2 Diarylamine novolac resin NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-02-16 US disclosed
US-20140235059-A1 DIARYLAMINE NOVOLAC RESIN NISSAN CHEMICAL INDUSTRIES, LTD (JP) 2014-08-21 US disclosed