Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.37 |
| ▸ | TLR2 | O60603 | 4/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.32 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15975507 | 0.87 | GLP1R (0.40) | GLP1RTLR2TGM2SIRT1SIRT6 | |
| SCHEMBL16216473 | 0.84 | GLP1R (0.41) | GLP1RTLR2TGM2SIRT1SIRT6 | |
| SCHEMBL14942519 | 0.79 | SIRT6 (0.47) | GLP1RTLR2SIRT1SIRT6 | |
| SCHEMBL837024 | 0.73 | GLP1R (0.42) | GLP1RTLR2SIRT1SIRT6SIRT2 | |
| SCHEMBL10310588 | 0.72 | GLP1R (0.41) | GLP1RTLR2TGM2SIRT1SIRT6 | |
| SCHEMBL10167191 | 0.71 | SIRT1 (0.43) | SIRT1SIRT6SIRT2SIRT3 | |
| SCHEMBL26346477 | 0.70 | GLP1R (0.46) | GLP1RTLR2SIRT1SIRT6SIRT2 | |
| SCHEMBL12410205 | 0.68 | SIRT1 (0.49) | SIRT1SIRT6SIRT2SIRT3 | |
| SCHEMBL15975505 | 0.67 | TGM2 (0.48) | TGM2SIRT1SIRT2SIRT3 | |
| SCHEMBL14642690 | 0.67 | SIRT2 (0.61) | TLR2SIRT1SIRT2SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815227-B2 | Hydroxyapatite-targeting multiarm polymers and conjugates made therefrom | NEKTAR THERAPEUTICS (US) | 2014-08-26 | — | — | US | disclosed |