Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | TLR2 | O60603 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15975507 | 0.89 | GLP1R (0.40) | GLP1RSIRT6SIRT1TLR2TGM2 | |
| SCHEMBL10167191 | 0.88 | SIRT1 (0.43) | SIRT6SIRT1EPHX1 | |
| SCHEMBL14942519 | 0.86 | SIRT6 (0.47) | GLP1RSIRT6SIRT1TLR2MEN1 | |
| SCHEMBL15975504 | 0.84 | GLP1R (0.37) | GLP1RSIRT6SIRT1TLR2TGM2 | |
| SCHEMBL13901982 | 0.76 | CPB1 (0.46) | GLP1RSIRT6SIRT1EPHX1TGM2 | |
| SCHEMBL13498644 | 0.76 | EPHX1 (0.53) | GLP1RSIRT6SIRT1EPHX1 | |
| SCHEMBL13498651 | 0.76 | EPHX1 (0.62) | GLP1RSIRT6SIRT1EPHX1 | |
| SCHEMBL13498646 | 0.76 | EPHX1 (0.57) | GLP1RSIRT6SIRT1EPHX1 | |
| SCHEMBL14262320 | 0.75 | SIRT1 (0.44) | GLP1RSIRT6SIRT1EPHX1 | |
| SCHEMBL13498562 | 0.74 | SIRT1 (0.46) | GLP1RSIRT6SIRT1EPHX1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9173947-B2 | Hydroxyapatite-targeting multiarm polymers and conjugates made therefrom | NEKTAR THERAPEUTICS (US) | 2015-11-03 | — | — | US | disclosed |
| US-20140329990-A1 | Hydroxyapatite-Targeting Multiarm Polymers and Conjugates Made Therefrom | NEKTAR THERAPEUTICS (US) | 2014-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140329990-A1 | Hydroxyapatite-Targeting Multiarm Polymers and Conjugates Made Therefrom | CD44, FGF23, PTH1R | GLP1R 2108/4885SIRT6 3369/4885SIRT1 4432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.