SCHEMBL16009783

SCHEMBL16009783

COCOc1cc(C)c(C2CCCCC2)c(OCOC)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ROR1 Q01973 1/20 0.36
PTGDR2 Q9Y5Y4 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CNR2 P34972 4/20 0.32
CNR1 P21554 3/20 0.32
PTGDR Q13258 1/20 0.30
PARP15 Q460N3 1/20 0.30
PARP10 Q53GL7 1/20 0.30
KDM4E B2RXH2 1/20 0.30
HDAC3 O15379 1/20 0.30
HDAC4 P56524 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC7 Q8WUI4 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC10 Q969S8 1/20 0.30
HDAC11 Q96DB2 1/20 0.30
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26874208 0.80 PTGDR2 (0.35) PTGDR2ALDH1A1CNR2CNR1KDM4E
SCHEMBL16018026 0.76 CNR2 (0.40) PTGDR2MEN1KMT2ACNR2CNR1
SCHEMBL24204617 0.75 CNR2 (0.37) PTGDR2CNR2CNR1PTGDR
SCHEMBL16009514 0.74 MAP2K3 (0.40) MEN1KMT2AALDH1A1CNR2CNR1
SCHEMBL24346128 0.72 FDPS (0.36) PTGDR2MEN1KMT2AALDH1A1NPSR1
SCHEMBL24204698 0.71 DRD2 (0.42) PTGDR2
SCHEMBL16010033 0.69 ALDH1A1 (0.38) ROR1ALDH1A1HDAC3HDAC4HDAC1
SCHEMBL29207265 0.69 ROR1 (0.34) ROR1ALDH1A1
SCHEMBL28603871 0.69 TNFRSF1A (0.38) ROR1MEN1KMT2AHDAC3HDAC4
SCHEMBL15114736 0.68 TNFRSF1A (0.40) ROR1MEN1KMT2AALDH1A1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10470986-B2 Resorcinol compounds for dermatological use CONOPCO, INC. (US) 2019-11-12 US disclosed
US-10470986-B2 Resorcinol compounds for dermatological use CONOPCO, INC. (US) 2019-11-12 US disclosed
EP-2964182-B1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER PLC A COMPANY REGISTERED IN ENGLAND AND WALES UNDER COMPANY NO 41424 OF (GB) 2018-02-14 EP disclosed
EP-2964182-B1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER PLC A COMPANY REGISTERED IN ENGLAND AND WALES UNDER COMPANY NO 41424 OF (GB) 2018-02-14 EP disclosed
EP-2964182-A2 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE Unilever PLC, a company registered in England and Wales under company no. 41424 of (GB) 2016-01-13 EP disclosed
US-20160000669-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE CONOPCO, INC., D/B/A UNILEVER (US) 2016-01-07 US disclosed
US-20160000669-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE CONOPCO, INC., D/B/A UNILEVER (US) 2016-01-07 US disclosed
US-20160000669-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE CONOPCO, INC., D/B/A UNILEVER (US) 2016-01-07 US disclosed
WO-2014138471-A2 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE AMPERE LIFE SCIENCES, INC. (US) 2014-09-12 WO disclosed
WO-2014138471-A2 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE AMPERE LIFE SCIENCES, INC. (US) 2014-09-12 WO disclosed
US-20140256830-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER N.V. (NL) 2014-09-11 US disclosed
US-20140256830-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER N.V. (NL) 2014-09-11 US disclosed
US-20140256830-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER N.V. (NL) 2014-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160000669-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE NQO1, RBP4, KEAP1 ROR1 725/4885PTGDR2 4453/4885MEN1 4079/4885
US-20140256830-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE NQO1, RBP4, KEAP1 ROR1 725/4885PTGDR2 4453/4885MEN1 4079/4885
US-10470986-B2 Resorcinol compounds for dermatological use NQO1, RBP4, KEAP1 ROR1 725/4885PTGDR2 4453/4885MEN1 4079/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.