Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL681184 | 0.81 | ELANE (0.34) | LMNAALDH1A1 | |
| SCHEMBL181730 | 0.80 | MIF (0.32) | LMNAMIFMMP8 | |
| SCHEMBL18925016 | 0.77 | ALDH1A1 (0.40) | LMNAALDH1A1MIF | |
| SCHEMBL23125481 | 0.76 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL6892214 | 0.76 | TSHR (0.43) | LMNAALDH1A1MMP8 | |
| SCHEMBL394513 | 0.76 | LMNA (0.36) | LMNAALDH1A1MIF | |
| SCHEMBL10253729 | 0.76 | PRKCA (0.42) | ALDH1A1MMP8 | |
| SCHEMBL12044962 | 0.75 | NAAA (0.41) | LMNAALDH1A1 | |
| SCHEMBL15694063 | 0.74 | DGKA (0.39) | LMNAALDH1A1MIF | |
| SCHEMBL8560408 | 0.74 | TSHR (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256658-A1 | Antibiotic Conjugates | ALLERGAN, INC. (US) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256658-A1 | Antibiotic Conjugates | NAALAD2, DNPEP, ENGASE | LMNA 3465/4885ALDH1A1 641/4885MIF 3573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.