Pyrophosphoric Acid

Pyrophosphoric Acid

SCHEMBL160240

O.O.O.O.O.O.O.O.O.O.O=P([O-])([O-])OP(=O)([O-])[O-].[Na+].[Na+].[Na+].[Na+]

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FDPS known ✓ P14324 1/20 0.31
LMNA P02545 1/20 0.35
CA1 P00915 2/20 0.35
CA4 P22748 2/20 0.35
CA5A P35218 2/20 0.35
CA5B Q9Y2D0 2/20 0.35
SLC34A1 Q06495 1/20 0.33
BLM P54132 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
BTN3A1 O00481 1/20 0.30
KDM4E B2RXH2 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrophosphoric Acid SCHEMBL11321543 1.00 LMNA (0.35) LMNACA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL10830790 1.00 LMNA (0.35) LMNACA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL1701116 1.00 LMNA (0.35) LMNACA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL28407584 1.00 LMNA (0.35) LMNACA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL593766 1.00 LMNA (0.35) LMNACA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL3465536 1.00 LMNA (0.35) LMNACA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL3968384 1.00 LMNA (0.35) LMNACA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL28409467 1.00 LMNA (0.35) LMNACA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL22749765 1.00 LMNA (0.35) LMNACA1CA4CA5ACA5B
Pyrophosphoric Acid SCHEMBL2893358 0.96 CA1 (0.33) LMNACA1CA4CA5ACA5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2185 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122012031-A Organic-inorganic hydrated salt composite phase-change material, and preparation method and application thereof 广东工业大学 2026-05-12 CN claimed
CN-121196929-B Tooth whitening composition with good storage stability and preparation method thereof 皓白(浙江)医疗器械有限公司 2026-02-27 CN claimed
EP-3558221-B1 HAIR LIGHTENING COMPOSITION COMPRISING HYDROGEN PEROXIDE, BICARBONATE, AND AT LEAST 0.5% BY WEIGHT OF POLYPHOSPHORUS DERIVATIVE OREAL (FR) 2025-10-15 EP claimed
EP-3558219-B1 HAIR LIGHTENING COMPOSITION COMPRISING AN OXIDIZING AGENT, A CARBONATE AND AT LEAST 0.5% BY WEIGHT OF POLYPHOSPHORUS DERIVATIVE OREAL (FR) 2025-10-15 EP claimed
US-20250257291-A1 PARTICULATE LAUNDRY SCENT ADDITIVE COMPRISING A PERFUME/WATER-SOLUBLE POLYMER/SALT HYDRATE MATRIX PROCTER & GAMBLE (US) 2025-08-14 US claimed
EP-4581064-A1 PREPARATION OF SILANE-GRAFTED EPDM AND MOISTURE CURING THEREOF Airboss of America Corp. (CA) 2025-07-09 EP claimed
CN-120158242-A Fluorine-containing binder for sulfide all-solid-state battery, and preparation method and application thereof 上海屹锂新能源科技有限公司 2025-06-17 CN claimed
WO-2025122837-A1 METHOD TO IMPROVE FIRE-RESISTANCE OF WOOD COMPOSITES, CELLULAR SOLIDS AND POROUS MATERIALS VIRGINIA COMMONWEALTH UNIVERSITY (US) 2025-06-12 WO claimed
US-12312567-B2 Particulate laundry scent additive comprising a polyethylene glycol/ethoxylated alcohol polymer composition THE PROCTER & GAMBLE COMPANY (US) 2025-05-27 US claimed
CN-119976773-A Preparation method and application of positive electrode material 合肥国轩高科动力能源有限公司 2025-05-13 CN claimed
EP-0140467-B1 HEAT STORAGE COMPOSITIONS Albright & Wilson Limited (GB) 1989-05-31 EP claimed
EP-0101181-B1 HEAT STORAGE MATERIALS, AND METHOD OF HEAT EXCHANGE THEREWITH IC GAS INTERNATIONAL LIMITED (GB) 1986-02-12 EP claimed
US-4545916-A Heat storage materials IC GAS INTERNATIONAL LIMITED (GB) 1985-10-08 US claimed
EP-0140467-A1 Heat storage compositions Albright & Wilson Limited (GB) 1985-05-08 EP claimed
EP-0049092-B1 HEAT ACCUMULATING MATERIAL MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1984-05-09 EP claimed
EP-0101181-A1 Heat storage materials, and method of heat exchange therewith IC GAS INTERNATIONAL LIMITED (GB) 1984-02-22 EP claimed
US-4406804-A Heat accumulating material MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1983-09-27 US claimed
US-4388194-A ALKALI POLYPHOSPHATE TO PREVENT DEPOSITION OF SLUDGE FMC CORPORATION (US) 1983-06-14 US claimed
US-4381245-A Supercooling inhibitor and process for preparing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1983-04-26 US claimed
US-4315078-A Flame retardant flexible polyurethane foam containing finely divided inorganic salt wherein a mold of said salt contains at least five moles of water THE UPJOHN COMPANY (US) 1982-02-09 US claimed