Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS known ✓ | P14324 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL11321543 | 1.00 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL10830790 | 1.00 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL1701116 | 1.00 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL28407584 | 1.00 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL593766 | 1.00 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL3968384 | 1.00 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL160240 | 1.00 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL28409467 | 1.00 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL22749765 | 1.00 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL2893358 | 0.96 | CA1 (0.33) | LMNACA1CA4CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4008705-A1 | METHOD FOR THE PREPARATION OF GRANULES CONTAINING POTASSIUM, MAGNESIUM AND SULPHATE | K+S Aktiengesellschaft (DE) | 2022-06-08 | — | — | EP | claimed |
| EP-3507246-A1 | PROCESS FOR PRODUCING POTASSIUM CHLORIDE GRANULATES | K+S Aktiengesellschaft (DE) | 2019-07-10 | — | — | EP | claimed |
| EP-2217663-A1 | POLYPHOSPHATE MODIFIER FOR WARM ASPHALT APPLICATIONS | ICL Performance Products LP (US) | 2010-08-18 | — | — | EP | claimed |
| US-7713345-B2 | \"warm\" asphalt paving composition that contains modified asphalt binder and aggregate, wherein the asphalt binder is modified, at least in part, by the addition of a hydrated phosphate modifier to the asphalt; allows for a decrease in the temperature used to mix and pave (compact) asphalt | ICL PERFORMANCE PRODUCTS, LP (US) | 2010-05-11 | — | — | US | claimed |
| WO-2009100356-A1 | POLYPHOSPHATE MODIFIER FOR WARM ASPHALT APPLICATIONS | ICL PERFORMANCE PRODUCTS LP (US) | 2009-08-13 | — | — | WO | claimed |
| US-20090194002-A1 | \"warm\" asphalt paving composition that contains modified asphalt binder and aggregate, wherein the asphalt binder is modified, at least in part, by the addition of a hydrated phosphate modifier to the asphalt; allows for a decrease in the temperature used to mix and pave (compact) asphalt | ICL PERFORMANCE PRODUCTS, LP (US) | 2009-08-06 | — | — | US | claimed |
| CN-113603833-B | Alkyd-acrylic hybrid emulsion and preparation method thereof | 珠海展辰新材料股份有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-118561258-A | Iron-based polyphosphate material with uniform mesoporous structure, preparation and application | 华中科技大学 | 2024-08-30 | — | — | CN | disclosed |
| CN-111978486-B | Polyacrylate emulsion and preparation method thereof | 濮阳展辰新材料有限公司 | 2024-02-27 | — | — | CN | disclosed |
| US-11795060-B2 | Process for producing potassium chloride granulates | K+S AKTIENGESELLSCHAFT (DE) | 2023-10-24 | — | — | US | disclosed |
| US-11631565-B2 | Thermal fuse | SCIENCE APPLICATIONS INTERNATIONAL CORPORATION (US) | 2023-04-18 | — | — | US | disclosed |
| EP-4008705-A1 | METHOD FOR THE PREPARATION OF GRANULES CONTAINING POTASSIUM, MAGNESIUM AND SULPHATE | K+S Aktiengesellschaft (DE) | 2022-06-08 | — | — | EP | disclosed |
| US-20220165529-A1 | Thermal Fuse | CITIBANK, N.A., AS COLLATERAL AGENT | 2022-05-26 | — | — | US | disclosed |
| US-20090194002-A1 | \"warm\" asphalt paving composition that contains modified asphalt binder and aggregate, wherein the asphalt binder is modified, at least in part, by the addition of a hydrated phosphate modifier to the asphalt; allows for a decrease in the temperature used to mix and pave (compact) asphalt | ICL PERFORMANCE PRODUCTS, LP (US) | 2009-08-06 | — | — | US | disclosed |
| US-5723105-A | ALKALI METAL ALKYL ETHER SULFATE | COLGATE-PALMOLIVE COMPANY (US) | 1998-03-03 | — | — | US | disclosed |
| EP-0549287-B1 | Visually clear gel dentifrice | COLGATE PALMOLIVE CO (US) | 1997-03-19 | — | — | EP | disclosed |
| US-5599526-A | HAVING ANIONIC SURFACTANT CONTAINING A POLYOXYETHYLE ALCOHOL SULFATE AND/OR ALKALI LAURYL SULFATE, OR MIXTURE OF ALKALI LAURYL SULFATE AND AN N-ACYL-N-ALKYLTAURATE; NONCRYSTALLIZING AT LOW TEMPERTURES | COLGATE-PALMOLIVE COMPANY | 1997-02-04 | — | — | US | disclosed |
| US-5354550-A | Comprising a polishing agent with a refractive index of 1.41 to 1.47, a water-swellable carboxy-containing anionic polymer; water, a humectant and 30% by weight sorbitol; stability | COLGATE PALMOLIVE COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
| US-5252313-A | Comprising water, sorbitol humectants and synthetic anionic copolymer; refractive index, clarity, stability | COLGATE-PALMOLIVE COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0549287-A1 | Visually clear gel dentifrice | Colgate-Palmolive Company (US) | 1993-06-30 | — | — | EP | disclosed |