Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7897758 | 0.84 | ALDH1A1 (0.38) | LTA4HCYP2D6RIPK1CA4L3MBTL1 | |
| SCHEMBL8946199 | 0.80 | PPARA (0.41) | LTA4HPREPPPARA | |
| SCHEMBL8983426 | 0.79 | PREP (0.36) | LTA4HCYP2D6RIPK1CA4L3MBTL1 | |
| SCHEMBL2368966 | 0.76 | PREP (0.45) | LTA4HCYP2D6RIPK1CA4L3MBTL1 | |
| SCHEMBL8210276 | 0.75 | — | — | |
| Methylamine SCHEMBL7237290 | 0.72 | PREP (0.42) | LTA4HCYP2D6RIPK1CA4L3MBTL1 | |
| SCHEMBL2398717 | 0.71 | LTA4H (0.41) | LTA4HRIPK1CA4L3MBTL1NPSR1 | |
| SCHEMBL977952 | 0.71 | KCNA3 (0.46) | LTA4HCA4L3MBTL1CHRNB2CHRNB4 | |
| SCHEMBL431273 | 0.69 | CA4 (0.42) | LTA4HCA4L3MBTL1CHRNB2CHRNB4 | |
| SCHEMBL1452863 | 0.68 | LTA4H (0.39) | LTA4HRIPK1CA4L3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2971023-A2 | METHODS OF USING NATURAL AND ENGINEERED ORGANISMS TO PRODUCE SMALL MOLECULES FOR INDUSTRIAL APPLICATION | Kiverdi, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014145194-A2 | METHODS OF USING NATURAL AND ENGINEERED ORGANISMS TO PRODUCE SMALL MOLECULES FOR INDUSTRIAL APPLICATION | KIVERDI, INC. (US) | 2014-09-18 | — | — | WO | disclosed |