Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318210 | 0.81 | PPARA (0.47) | PPARAPPARGLTA4HELANEPTGER4 | |
| SCHEMBL16061102 | 0.80 | LTA4H (0.35) | PPARALTA4HPREP | |
| SCHEMBL16301942 | 0.73 | LTA4H (0.48) | PPARAPPARGLTA4HELANEPTGER4 | |
| SCHEMBL7897758 | 0.71 | ALDH1A1 (0.38) | PPARALTA4HPREP | |
| SCHEMBL9813447 | 0.69 | PPARA (0.38) | PPARAESR1ESR2 | |
| SCHEMBL12426281 | 0.68 | PREP (0.46) | PREP | |
| SCHEMBL2882151 | 0.68 | PPARA (0.50) | PPARAPREP | |
| SCHEMBL14764352 | 0.68 | CA12 (0.52) | PPARAPPARGPREP | |
| SCHEMBL14384880 | 0.67 | PREP (0.45) | ELANEPREP | |
| SCHEMBL15596696 | 0.67 | HRH3 (0.43) | PPARAPPARGLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5561119-A | ANTITUMOR AGENTS | LABORATOIRES HOECHST (FR) | 1996-10-01 | — | — | US | disclosed |