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SCHEMBL16076284

SCHEMBL16076284

CCCN(C)CCNC(=O)CCN1CCC(C2CCN(CCC(=O)NC)CC2)CC1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.38
▸ HTT P42858 1/20 0.38
▸ LMNA P02545 2/20 0.36
▸ DNM1 Q05193 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ KMT2A Q03164 2/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ HSD17B10 Q99714 2/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ GNAI3 P08754 1/20 0.34
▸ GNAO1 P09471 1/20 0.34
▸ GNAI1 P63096 1/20 0.34
▸ L3MBTL1 Q9Y468 2/20 0.34
▸ TP53 P04637 2/20 0.34
▸ GAA P10253 1/20 0.34
▸ ALDH1A1 P00352 2/20 0.33
▸ HTR4 Q13639 1/20 0.33
▸ TERT O14746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16076286 0.88 USP2 (0.43) POLBHTTDNM1KMT2AMEN1
SCHEMBL16077706 0.86 POLB (0.48) POLBHTTLMNAMAPTKMT2A
SCHEMBL16077705 0.83 GNAI3 (0.43) POLBHTTMAPTSMN1; SMN2GNAI3
SCHEMBL16077707 0.82 GNAI3 (0.48) POLBHTTGNAI3GNAO1GNAI1
SCHEMBL23776430 0.80 SIGMAR1 (0.36) POLBHTTLMNAMAPTHSD17B10
SCHEMBL16076285 0.79 OPRD1 (0.42) POLBHTTMAPTSMN1; SMN2GNAI3
SCHEMBL19519931 0.75 POLB (0.39) POLBHTTLMNAMAPTHSD17B10
SCHEMBL16122917 0.72 ALDH1A1 (0.46) POLBHTTGNAI3GNAO1GNAI1
SCHEMBL19519932 0.71 POLB (0.36) POLBHTTLMNADNM1MAPT
SCHEMBL24703407 0.71 SMN1; SMN2 (0.39) POLBHTTLMNADNM1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170296577-A1 Multi-dose Compositions Containing an Antimicrobial Polyamide or Octenidine Preservative MERIAL INC. (US) 2017-10-19 — — US disclosed
US-20160208046-A1 AMINE FUNCTIONAL POLYAMIDES GENZYME CORPORATION 2016-07-21 — — US disclosed
US-9326994-B2 Amine functional polyamides GENZYME CORPORATION (US) 2016-05-03 — — US disclosed
US-20140275469-A1 AMINE FUNCTIONAL POLYAMIDES GENZYME CORPORATION (US) 2014-09-18 — — US disclosed
US-20140271526-A1 ANTIMICROBIAL POLYAMIDE COMPOSITIONS AND MASTITIS TREATMENT MERIAL LIMITED (US) 2014-09-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170296577-A1 Multi-dose Compositions Containing an Antimicrobial Polyamide or Octenidine Preservative NONO, PUF60, ERP29 POLB 962/4885HTT 85/4885LMNA 1631/4885
US-20160208046-A1 AMINE FUNCTIONAL POLYAMIDES PAM, ASNS, PARN POLB 147/4885HTT 4031/4885LMNA 3835/4885
US-20140271526-A1 ANTIMICROBIAL POLYAMIDE COMPOSITIONS AND MASTITIS TREATMENT PUF60, PARG, PAM POLB 514/4885HTT 2837/4885LMNA 2403/4885
US-20140275469-A1 AMINE FUNCTIONAL POLYAMIDES PAM, ASNS, PARN POLB 147/4885HTT 4031/4885LMNA 3835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.