SCHEMBL1608945

SCHEMBL1608945

CC(F)(C(=O)F)C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3837157 0.74
SCHEMBL8072630 0.74
SCHEMBL8072632 0.74
SCHEMBL11825149 0.73 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL16218313 0.73 LMNA (0.31) ALDH1A1TSHR
SCHEMBL1790667 0.73 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL8416761 0.73 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL421936 0.73 MEN1 (0.31) ALDH1A1TSHR
SCHEMBL11047183 0.73
SCHEMBL10309581 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109020778-A The manufacturing method of dry etching gases 大金工业株式会社 2018-12-18 CN disclosed
CN-109020778-A The manufacturing method of dry etching gases 大金工业株式会社 2018-12-18 CN disclosed
EP-2483361-B1 APPARATUS INCLUDING HYDROFLUOROETHER WITH HIGH TEMPERATURE STABILITY AND USES THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2016-05-25 EP disclosed
US-8981162-B2 Method for preparing fluorine-containing vinyl ether ZHONGHAO CHENGUANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY COMPANY LIMITED (CN) 2015-03-17 US disclosed
US-20140330046-A1 Method for Preparing Fluorine-Containing Vinyl Ether ZHONGHAO CHENGUANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY COMPANY LIMITED (CN) 2014-11-06 US disclosed
US-8591761-B2 Apparatus including hydrofluoroether with high temperature stability and uses thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-11-26 US disclosed
US-8535559-B2 Nitrogen-containing fluoroketones for high temperature heat transfer 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-09-17 US disclosed
US-8323524-B2 Apparatus including hydrofluoroether with high temperature stability and uses thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-12-04 US disclosed
US-20120298333-A1 APPARATUS INCLUDING HYDROFLUOROETHER WITH HIGH TEMPERATURE STABILITY AND USES THEREOF 3M INNOVATIVE PROPERTIES COMPANY 2012-11-29 US disclosed
EP-2483361-A2 APPARATUS INCLUDING HYDROFLUOROETHER WITH HIGH TEMPERATURE STABILITY AND USES THEREOF 3M Innovative Properties Company (US) 2012-08-08 EP disclosed
US-20110232870-A1 NITROGEN-CONTAINING FLUOROKETONES FOR HIGH TEMPERATURE HEAT TRANSFER 3M INNOVATION PROPERTIES COMPANY 2011-09-29 US disclosed
WO-2011041208-A2 APPARATUS INCLUDING HYDROFLUOROETHER WITH HIGH TEMPERATURE STABILITY AND USES THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-04-07 WO disclosed
US-20110079043-A1 APPARATUS INCLUDING HYDROFLUOROETHER WITH HIGH TEMPERATURE STABILITY AND USES THEREOF 3M INNOVATIVE PROPERTIES COMPANY 2011-04-07 US disclosed
US-7449266-B2 Perfluoropolyether benzotriazole compounds 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-11-11 US disclosed
WO-2007056561-A2 MEDICAL DEVICE, MATERIALS, AND METHODS LIQUIDIA TECHNOLOGIES, INC. (US) 2007-05-18 WO disclosed
US-20070048673-A1 PERFLUOROPOLYETHER BENZOTRIAZOLE COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY 2007-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070048673-A1 PERFLUOROPOLYETHER BENZOTRIAZOLE COMPOUNDS GABBR1, PAOX, GABRG1 ALDH1A1 2101/4885TSHR 1144/4885
US-20110232870-A1 NITROGEN-CONTAINING FLUOROKETONES FOR HIGH TEMPERATURE HEAT TRANSFER FN3KRP, HSF1, NEK1 ALDH1A1 1280/4885TSHR 4196/4885
US-20140330046-A1 Method for Preparing Fluorine-Containing Vinyl Ether PFAS, VGF, PLD4 ALDH1A1 1661/4885TSHR 2421/4885
US-20120298333-A1 APPARATUS INCLUDING HYDROFLUOROETHER WITH HIGH TEMPERATURE STABILITY AND USES THEREOF HSF1, SLC46A1, HSP90AA1 ALDH1A1 2575/4885TSHR 2909/4885
US-20110079043-A1 APPARATUS INCLUDING HYDROFLUOROETHER WITH HIGH TEMPERATURE STABILITY AND USES THEREOF HSF1, SLC46A1, HSP90AA1 ALDH1A1 2575/4885TSHR 2909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.