SCHEMBL16097482

SCHEMBL16097482

C[Si](C)(C)c1cccc2[nH][c]nc12

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1264261 0.72 TDP1 (0.40)
SCHEMBL558260 0.72 PARP1 (0.34)
SCHEMBL1886180 0.72 PSMB8 (0.41)
SCHEMBL127276 0.72 ACHE (0.40)
SCHEMBL4623912 0.72 METAP2 (0.35)
SCHEMBL407499 0.72 PSMD14 (0.36)
SCHEMBL1888862 0.72 AXL (0.43)
SCHEMBL557929 0.72 KEAP1 (0.44)
SCHEMBL7309866 0.72 GABRA1 (0.38)
SCHEMBL9110854 0.67 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2969593-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES Bridgestone Corporation (JP) 2016-01-20 EP claimed
WO-2014149931-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES BRIDGESTONE CORPORATION (JP) 2014-09-25 WO claimed