SCHEMBL1610345

SCHEMBL1610345

[CH2]CCCCCCCc1ccc2ccccc2c1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.56
HDAC1 Q13547 1/20 0.55
HDAC8 Q9BY41 1/20 0.55
CYP1A2 P05177 2/20 0.54
CYP2A6 P11509 1/20 0.48
HRH3 Q9Y5N1 1/20 0.46
NAAA Q02083 1/20 0.46
HCAR2 Q8TDS4 1/20 0.43
MC4R P32245 1/20 0.43
MC5R P33032 1/20 0.43
HSP90AB1 P08238 1/20 0.43
SLC6A4 P31645 1/20 0.42
BCHE P06276 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL129049 1.00 SIGMAR1 (0.56) SIGMAR1HDAC1HDAC8CYP1A2CYP2A6
SCHEMBL1610472 1.00 SIGMAR1 (0.56) SIGMAR1HDAC1HDAC8CYP1A2CYP2A6
SCHEMBL27523237 0.98 SIGMAR1 (0.54) SIGMAR1HDAC1HDAC8CYP1A2CYP2A6
SCHEMBL133399 0.98 SIGMAR1 (0.58) SIGMAR1HDAC1HDAC8CYP1A2CYP2A6
SCHEMBL1611043 0.94 SIGMAR1 (0.50) SIGMAR1HDAC1HDAC8CYP1A2CYP2A6
SCHEMBL1610204 0.94 SIGMAR1 (0.50) SIGMAR1HDAC1HDAC8CYP1A2CYP2A6
SCHEMBL1612447 0.94 SIGMAR1 (0.50) SIGMAR1HDAC1HDAC8CYP1A2CYP2A6
SCHEMBL1611323 0.92 SIGMAR1 (0.51) SIGMAR1HDAC1HDAC8CYP1A2CYP2A6
SCHEMBL128560 0.92 SIGMAR1 (0.59) SIGMAR1HDAC1HDAC8CYP1A2CYP2A6
SCHEMBL2092017 0.90 HDAC1 (0.48) SIGMAR1HDAC1HDAC8CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3178323-B1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2021-06-23 EP disclosed
EP-3020715-B1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2021-06-16 EP disclosed
EP-3239111-B1 CURABLE COMPOSITION, TRANSFER FILM, FRONT PLATE OF IMAGE DISPLAY DEVICE, FRONT PLATE-INTEGRATED SENSOR, IMAGE DISPLAY DEVICE, AND MANUFACTURING METHOD FOR FRONT PLATE OF IMAGE DISPLAY DEVICE FUJIFILM CORP (JP) 2021-02-17 EP disclosed
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed
EP-3040332-B1 TETRAZOLINONE COMPOUND AND USE OF SAME SUMITOMO CHEMICAL CO (JP) 2020-06-03 EP disclosed
US-10251396-B2 Amide compound and use of same for noxious arthropod control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-04-09 US disclosed
US-10035927-B2 Coloring composition for decoration, decorative material, base material having decorative material, transfer material, touch panel, and information display device FUJIFILM CORPORATION (JP) 2018-07-31 US disclosed
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
CN-105324373-B Tetrazolinone compound and use thereof 住友化学株式会社 2018-02-16 CN disclosed
US-9888688-B2 Tetrazolinone compounds and applications thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-13 US disclosed
WO-2013162072-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-10-31 WO disclosed
EP-2520570-A1 AMINOPYRIDINE COMPOUND Ube Industries, Ltd. (JP) 2012-11-07 EP disclosed
US-20120259123-A1 AMINOPYRIDINE COMPOUND UBE INDUSTRIES, LTD. (JP) 2012-10-11 US disclosed
CN-102666490-A Aminopyridine compound UBE INDUSTRIES 2012-09-12 CN disclosed
US-20120226036-A1 SUBSTITUTED CARBONYL COMPOUND UBE INDUSTRIES, LTD. (JP) 2012-09-06 US disclosed
EP-2476678-A1 SUBSTITUTED CARBONYL COMPOUNDS Ube Industries, Ltd. (JP) 2012-07-18 EP disclosed
US-20110087034-A1 Organic Semiconductor Material SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2011-04-14 US disclosed
EP-2248818-A1 ORGANIC SEMICONDUCTOR MATERIAL Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-0668259-A1 A method for the preparation of optically active 2-aryl alkyl aldehydes and formation of 2-aryl-alkanoic acids therefrom MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) 1995-08-23 EP disclosed
US-5434302-A Method for the preparation of optically active 2-aryl alkyl aldehydes and formation of 2-aryl-alkanoic acids therefrom PARADIES H HENRICH (DE) 1995-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120226036-A1 SUBSTITUTED CARBONYL COMPOUND PTGER2, PTGER1, LTB4R2 SIGMAR1 494/4885HDAC1 994/4885HDAC8 1664/4885
US-20120259123-A1 AMINOPYRIDINE COMPOUND PTGIS, QDPR, PTGIR SIGMAR1 2629/4885HDAC1 2557/4885HDAC8 3651/4885
US-20110087034-A1 Organic Semiconductor Material OR10J3, TST, OR51E2 SIGMAR1 223/4885HDAC1 2752/4885HDAC8 4616/4885
US-10251396-B2 Amide compound and use of same for noxious arthropod control OPRM1, TRPA1, L3MBTL3 SIGMAR1 28/4885HDAC1 826/4885HDAC8 1291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.