Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | FPR2 | P25090 | 4/20 | 0.38 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | PPIB | P23284 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21777316 | 0.84 | EPHX2 (0.45) | NPSR1KDM4EALDH1A1GAAPOLB | |
| SCHEMBL16111612 | 0.79 | ALDH1A1 (0.43) | MEN1KMT2AFPR2FPR3PROKR1 | |
| SCHEMBL16112282 | 0.77 | RORC (0.40) | MEN1KMT2AFPR2FPR3MAPK1 | |
| SCHEMBL11638898 | 0.75 | TUBB4A (0.40) | MEN1KMT2ASMN1; SMN2LMNANPSR1 | |
| SCHEMBL1980329 | 0.74 | POLB (0.49) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL16839826 | 0.72 | FPR2 (0.43) | MEN1KMT2AFPR2FPR3PROKR1 | |
| SCHEMBL16839934 | 0.71 | OPRM1 (0.44) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL21789124 | 0.71 | EPHX2 (0.47) | MEN1KMT2AMAPTNPSR1KDM4E | |
| SCHEMBL11641196 | 0.71 | SMN1; SMN2 (0.44) | MEN1KMT2AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL16838934 | 0.70 | SMN1; SMN2 (0.47) | MEN1KMT2ASMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014160649-A1 | HYDROXAMIC ACID DERIVATIVES AS LPXC INHIBITORS FOR THE TREATMENT OF BACTERIAL INFECTIONS | NOVARTIS AG (CH) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014160649-A1 | HYDROXAMIC ACID DERIVATIVES AS LPXC INHIBITORS FOR THE TREATMENT OF BACTERIAL INFECTIONS | NOVARTIS AG (CH) | 2014-10-02 | — | — | WO | disclosed |