Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.36 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13416287 | 0.93 | ACHE (0.43) | ACHECYP2D6GPR174P2RY10 | |
| SCHEMBL13416272 | 0.85 | PTGS2 (0.40) | — | |
| SCHEMBL16124574 | 0.84 | ALOX5 (0.48) | ACHECYP2D6TAAR1 | |
| SCHEMBL13416257 | 0.83 | ACHE (0.43) | ACHE | |
| SCHEMBL16124599 | 0.81 | PPARA (0.48) | ACHECYP2D6 | |
| SCHEMBL13396481 | 0.81 | ALOX5 (0.42) | ACHETAAR1ACACBACACA | |
| SCHEMBL13416416 | 0.81 | ACHE (0.41) | ACHE | |
| SCHEMBL13417055 | 0.79 | ACHE (0.40) | ACHE | |
| SCHEMBL13416281 | 0.78 | ACHE (0.44) | ACHETAAR1 | |
| SCHEMBL13417053 | 0.78 | SPHK1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2010-04-22 | — | — | US | disclosed |
| WO-2008095841-A2 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2008-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | ACHE 540/4885CYP2D6 1159/4885GPR174 1525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.