Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 14/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18272058 | 0.95 | CHRM3 (0.38) | L3MBTL1HTTCHRM3CHRM2CHRM1 | |
| SCHEMBL22213482 | 0.95 | L3MBTL1 (0.35) | L3MBTL1HTTCHRM3CHRM2CHRM1 | |
| SCHEMBL18269756 | 0.86 | LMNA (0.42) | L3MBTL1HTTMAPTALDH1A1KMT2A | |
| SCHEMBL16127934 | 0.84 | SCN1A (0.40) | KMT2AMEN1LMNA | |
| SCHEMBL20885165 | 0.82 | MTNR1A (0.33) | KMT2A | |
| SCHEMBL19712958 | 0.79 | CHRM3 (0.45) | L3MBTL1HTTCHRM3CHRM2CHRM1 | |
| SCHEMBL22213477 | 0.77 | CHRM3 (0.35) | L3MBTL1HTTCHRM3CHRM2CHRM1 | |
| SCHEMBL17036157 | 0.77 | LMNA (0.38) | L3MBTL1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL11920351 | 0.76 | MTNR1A (0.36) | HTT | |
| SCHEMBL11920353 | 0.76 | AR (0.41) | HTTMAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976323-B1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES CO (US) | 2020-07-15 | — | — | EP | disclosed |
| US-20190105237-A1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES CO (US) | 2019-04-11 | — | — | US | disclosed |
| US-10195119-B2 | High refractive index addition-fragmentation agents | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-02-05 | — | — | US | disclosed |
| US-9730864-B2 | Addition-fragmentation oligomers having high refractive index groups | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-08-15 | — | — | US | disclosed |
| US-20160346170-A1 | ADDITION-FRAGMENTATION OLIGOMERS HAVING HIGH REFRACTIVE INDEX GROUPS | 3M INNOVATIVE PROPERTIES COMPANY | 2016-12-01 | — | — | US | disclosed |
| US-20160279033-A1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2016-09-29 | — | — | US | disclosed |
| US-20160279033-A1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2016-09-29 | — | — | US | disclosed |
| WO-2014151363-A1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160346170-A1 | ADDITION-FRAGMENTATION OLIGOMERS HAVING HIGH REFRACTIVE INDEX GROUPS | ZYX, MACF1, PYCARD | L3MBTL1 2887/4885HTT 3723/4885CHRM3 3602/4885 |
| US-10195119-B2 | High refractive index addition-fragmentation agents | EEF1G, FANCI, EEF1E1 | L3MBTL1 3569/4885HTT 3800/4885CHRM3 4374/4885 |
| US-20160279033-A1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | EEF1G, FANCI, EEF1E1 | L3MBTL1 3569/4885HTT 3800/4885CHRM3 4374/4885 |
| US-20190105237-A1 | HIGH REFRACTIVE INDEX ADDITION-FRAGMENTATION AGENTS | EEF1G, FANCI, EEF1E1 | L3MBTL1 3569/4885HTT 3800/4885CHRM3 4374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.