Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.30 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.30 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.30 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.30 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.30 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.30 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456529 | 0.87 | ACHE (0.42) | ACHEALDH1A1CYP3A4PTPN1 | |
| SCHEMBL7951418 | 0.87 | ACHE (0.42) | ACHEALDH1A1KMT2AMEN1 | |
| SCHEMBL28761737 | 0.85 | ACHE (0.41) | ACHEALDH1A1CYP3A4PTPN1 | |
| SCHEMBL386286 | 0.83 | ACHE (0.39) | ACHE | |
| SCHEMBL1424328 | 0.83 | ACHE (0.39) | ACHEMAPT | |
| SCHEMBL19208027 | 0.83 | ACHE (0.39) | ACHEALDH1A1CYP3A4TDP1KMT2A | |
| SCHEMBL456298 | 0.79 | ACHE (0.37) | ACHE | |
| SCHEMBL4853131 | 0.79 | ABL1 (0.36) | ACHEALDH1A1CYP3A4TDP1MAPT | |
| SCHEMBL11503690 | 0.78 | ACHE (0.35) | ACHERECQL | |
| SCHEMBL19724 | 0.77 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10772874-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. | 2020-09-15 | — | — | US | claimed |
| US-10272072-B2 | Compounds and compositions for the inhibition of NAMPT | FORMA TM, LLC (US) | 2019-04-30 | — | — | US | claimed |
| US-20170368039-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | FORMA TM, LLC (US) | 2017-12-28 | — | — | US | claimed |
| US-20140294805-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | VALO EARLY DISCOVERY, INC. | 2014-10-02 | — | — | US | claimed |
| EP-2611804-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | Forma TM, LLC. (US) | 2013-07-10 | — | — | EP | claimed |
| WO-2012031197-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | FORMA THERAPEUTICS, INC. (US) | 2012-03-08 | — | — | WO | claimed |
| US-20040043995-A1 | Novel triazole derivatives, process for their preparation and pharmaceutical compositions containing them | BIGNON ERIC (FR) | 2004-03-04 | — | — | US | claimed |
| EP-0984960-B1 | N-TRIAZOLYL-2-INDOLECARBOXAMIDES AND THEIR USE AS CCK-A AGONISTS | SANOFI SYNTHELABO (FR) | 2003-02-05 | — | — | EP | claimed |
| EP-0984960-A1 | N-TRIAZOLYL-2-INDOLECARBOXAMIDES AND THEIR USE AS CCK-A AGONISTS | SANOFI-SYNTHELABO (FR) | 2000-03-15 | — | — | EP | claimed |
| WO-1998051686-A1 | N-TRIAZOLYL-2-INDOLECARBOXAMIDES AND THEIR USE AS CCK-A AGONISTS | SANOFI-SYNTHELABO (FR) | 1998-11-19 | — | — | WO | claimed |
| US-5656648-A | TREATMENT OF PATHOLOGIES NECESSITATING STIMULATION OF CHOLECYSTOKININ-A RECEPTORS BY TOTAL OR PARTIAL AGONIST EFFECT | SANOFI (FR) | 1997-08-12 | — | — | US | claimed |
| EP-0611766-A1 | Polysubstituted 2-amido thiazoles derivatives, process for their preparation, pharmaceutical compositions and utilization for the preparation of a medicament | SANOFI (FR) | 1994-08-24 | — | — | EP | claimed |
| JP-6070774-A | — | — | None | — | — | JP | disclosed |
| US-20240208923-A1 | SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION | JNANA THERAPEUTICS INC. | 2024-06-27 | — | — | US | disclosed |
| CN-113896607-B | Olefin oligomerization process using a catalyst comprising a chromium complex having a phosphacycle-containing ligand | 陶氏环球技术有限责任公司 | 2024-04-16 | — | — | CN | disclosed |
| US-11896965-B2 | Chromium complex and catalyst therefrom | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-02-13 | — | — | US | disclosed |
| JP-H0670774-A | RIBOZYME HAVING THERMODYNAMICALLY STABLE LOOP STRUCTURE | SANKYO CO LTD | 1994-03-15 | — | — | JP | disclosed |
| EP-0560724-A1 | Benzoyl substituted phosphabicycloalcanes and their sulphides as photoinitiators | CIBA-GEIGY AG (CH) | 1993-09-15 | — | — | EP | disclosed |
| EP-0450637-A2 | Direct positive color image forming method | FUJI PHOTO FILM CO., LTD. (JP) | 1991-10-09 | — | — | EP | disclosed |
| JP-H00670774-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043995-A1 | Novel triazole derivatives, process for their preparation and pharmaceutical compositions containing them | CCKAR, CCKBR, NPY1R | ACHE 3455/4885ALDH1A1 2097/4885TSHR 197/4885 |
| US-20240208923-A1 | SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION | SLC18A2, SLC6A19, SLC1A1 | ACHE 4763/4885ALDH1A1 1257/4885TSHR 2258/4885 |
| US-20170368039-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | NAMPT, NNMT, NQO1 | ACHE 1026/4885ALDH1A1 1273/4885TSHR 2455/4885 |
| US-20140294805-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | NAMPT, NNMT, NQO1 | ACHE 1026/4885ALDH1A1 1273/4885TSHR 2455/4885 |
| US-10772874-B2 | Compounds and compositions for the inhibition of NAMPT | NAMPT, NNMT, NQO1 | ACHE 890/4885ALDH1A1 994/4885TSHR 2846/4885 |
| US-11896965-B2 | Chromium complex and catalyst therefrom | OXER1, LIG1, PICALM | ACHE 110/4885ALDH1A1 4013/4885TSHR 4123/4885 |
| US-10272072-B2 | Compounds and compositions for the inhibition of NAMPT | NAMPT, NNMT, NQO1 | ACHE 890/4885ALDH1A1 994/4885TSHR 2846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.