SCHEMBL1615076

SCHEMBL1615076

COc1cccc(-c2cccc3c4ccccc4c4ccccc4c23)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.55
CYP1A2 P05177 5/20 0.48
CYP2C9 P11712 5/20 0.48
CYP2B6 P20813 5/20 0.48
CYP3A4 P08684 4/20 0.48
AHR P35869 3/20 0.48
NR1I3 Q14994 3/20 0.48
VDR P11473 2/20 0.48
CYP2D6 P10635 3/20 0.47
CYP1A1 P04798 2/20 0.47
CYP2E1 P05181 2/20 0.47
CYP2C8 P10632 2/20 0.47
CYP2A6 P11509 2/20 0.47
CYP4B1 P13584 2/20 0.47
CYP3A5 P20815 2/20 0.47
CYP2A7 P20853 2/20 0.47
CYP3A7 P24462 2/20 0.47
CYP2F1 P24903 2/20 0.47
CYP2C18 P33260 2/20 0.47
CYP2C19 P33261 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2020140 0.85 ABL1 (0.59) BRD4CYP1A2CYP2C9CYP2B6CYP3A4
SCHEMBL3644450 0.83 BRD4 (0.50) BRD4CYP1A2CYP2C9CYP2B6CYP3A4
SCHEMBL5286981 0.82 BRD4 (0.55) BRD4CYP1A2CYP2C9CYP2B6CYP3A4
SCHEMBL3455245 0.81 ABL1 (0.60) BRD4CYP1A2CYP2C9CYP2B6CYP3A4
SCHEMBL13211663 0.81 ABL1 (0.60) BRD4CYP1A2CYP2C9CYP2B6CYP3A4
SCHEMBL9538506 0.81 GPR84 (0.59) BRD4CYP1A2CYP2C9CYP2B6CYP3A4
SCHEMBL13241129 0.79 BRD4 (0.51) BRD4CYP1A2CYP2C9CYP2B6CYP3A4
SCHEMBL29021327 0.78 BRD4 (0.38) BRD4GPR84SERPINE1MAOBALDH1A1
SCHEMBL1615035 0.78 CYP1A2 (0.53) BRD4CYP1A2CYP2C9CYP2B6CYP3A4
SCHEMBL2809119 0.78 CYP1A2 (0.53) BRD4CYP1A2CYP2C9CYP2B6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230320196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-11690286-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-27 US disclosed
US-20210167292-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-06-03 US disclosed
US-10957858-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-03-23 US disclosed
US-20190245147-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-08-08 US disclosed
US-10312450-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-06-04 US disclosed
EP-3424918-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES Universal Display Corporation (US) 2019-01-09 EP disclosed
EP-3112336-B1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORP (US) 2018-08-01 EP disclosed
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-20140291638-A1 HOST MATERIALS FOR OLED APPLICATION UNIVERSAL DISPLAY CORPORATION (US) 2014-10-02 US disclosed
US-20140291638-A1 HOST MATERIALS FOR OLED APPLICATION UNIVERSAL DISPLAY CORPORATION (US) 2014-10-02 US disclosed
US-20140291638-A1 HOST MATERIALS FOR OLED APPLICATION UNIVERSAL DISPLAY CORPORATION (US) 2014-10-02 US disclosed
US-20140103327-A1 HOST MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2014-04-17 US disclosed
US-8652652-B2 Single triphenylene chromophores in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2014-02-18 US disclosed
EP-2200956-B1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORP (US) 2013-07-03 EP disclosed
EP-2511254-A2 Single triphenylene chromophores in phosphorescent light emitting diodes Universal Display Corporation (US) 2012-10-17 EP disclosed
US-20110084599-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2011-04-14 US disclosed
EP-2200956-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES Universal Display Corporation (US) 2010-06-30 EP disclosed
WO-2009021107-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10312450-B2 Organic electroluminescent materials and devices NONO, ORC3, LEF1 BRD4 1824/4885CYP1A2 938/4885CYP2C9 1174/4885
US-20110084599-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES TYR, PNP, MAPRE2 BRD4 163/4885CYP1A2 3438/4885CYP2C9 2395/4885
US-20230320196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NONO, ORC3, TYR BRD4 1120/4885CYP1A2 1266/4885CYP2C9 1489/4885
US-10957858-B2 Organic electroluminescent materials and devices NONO, ORC3, LEF1 BRD4 1824/4885CYP1A2 938/4885CYP2C9 1174/4885
US-11690286-B2 Organic electroluminescent materials and devices NONO, ORC3, LEF1 BRD4 1824/4885CYP1A2 938/4885CYP2C9 1174/4885
US-20210167292-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NONO, ORC3, LEF1 BRD4 1824/4885CYP1A2 938/4885CYP2C9 1174/4885
US-20190245147-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NONO, ORC3, LEF1 BRD4 1824/4885CYP1A2 938/4885CYP2C9 1174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.