Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28909345 | 0.89 | HTR2A (0.46) | HTR2ARAB9AHTTALDH1A1MAOB | |
| SCHEMBL37664 | 0.87 | HTR2A (0.62) | HTR2ARAB9AIDO1AKR1C3HTT | |
| SCHEMBL9208980 | 0.83 | HTR2A (0.56) | HTR2ARAB9AIDO1AKR1C3HTT | |
| SCHEMBL9676749 | 0.81 | HTR2A (0.57) | HTR2ARAB9AIDO1AKR1C3HTT | |
| SCHEMBL6645015 | 0.81 | RAB9A (0.61) | HTR2ARAB9AIDO1AKR1C3HTT | |
| SCHEMBL4725847 | 0.81 | HTR2A (0.59) | HTR2ARAB9AIDO1AKR1C3HTT | |
| SCHEMBL1029307 | 0.81 | HTR2A (0.59) | HTR2ARAB9AIDO1AKR1C3HTT | |
| SCHEMBL11000854 | 0.81 | HTR2A (0.53) | HTR2ARAB9AIDO1AKR1C3HTT | |
| SCHEMBL30086 | 0.81 | HTR2A (0.56) | HTR2ARAB9AALDH1A1TGM2MAPT | |
| SCHEMBL8571160 | 0.80 | IDO1 (0.53) | HTR2ARAB9AIDO1AKR1C3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1823 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2991655-B1 | COMPOSITIONS AND METHODS FOR ALTERING SECOND MESSENGER SIGNALING | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2024-04-10 | — | — | EP | claimed |
| EP-3606528-B1 | TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF | BROAD INST INC (US) | 2023-10-18 | — | — | EP | claimed |
| EP-3092220-B1 | VITAMIN C PRODRUGS AND USES THEREOF | UNIV FLORIDA (US) | 2021-01-20 | — | — | EP | claimed |
| US-10870651-B2 | Inhibitors of cyclin-dependent kinase 7 (CDK7) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-12-22 | — | — | US | claimed |
| EP-2016044-B1 | PENTACYCLINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS | HARVARD COLLEGE (US) | 2020-06-10 | — | — | EP | claimed |
| EP-3063164-B1 | SYNTHETIC ROUTE TO 2'-DEOXY-2',2'-DIFLUOROTETRAHYDROURIDINES | OTSUKA PHARMA CO LTD (JP) | 2018-12-05 | — | — | EP | claimed |
| US-9856225-B2 | Substituted phenazines as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-01-02 | — | — | US | claimed |
| EP-2550285-B1 | TRIOXACARCINS AND USES THEREOF | HARVARD COLLEGE (US) | 2017-07-19 | — | — | EP | claimed |
| US-20150376201-A1 | CORTISTATIN ANALOGUES AND SYNTHESES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-12-31 | — | — | US | claimed |
| US-12037355-B2 | Triterpene saponin analogues | ADJUVANCE TECHNOLOGIES, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| CN-118355117-A | Oligonucleotide compositions and methods thereof | 波涛生命科学有限公司 | 2024-07-16 | — | — | CN | disclosed |
| US-20240229026-A1 | CHIRAL CONTROL | WAVE LIFE SCIENCES LTD. (SG) | 2024-07-11 | — | — | US | disclosed |
| WO-2024147060-A1 | NOVEL IONIZABLE LIPID COMPOUNDS FOR NUCLEIC ACID DELIVERY | CELON PHARMA S.A. (PL) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2007008226-A9 | PALLADIUM-CATALYZED CARBON-CARBON BOND FORMING REACTIONS | HARVARD COLLEGE (US) | 2007-05-24 | — | — | WO | disclosed |
| US-20070066851-A1 | Palladium-catalyzed carbon-carbon bond forming reactions | NAVY, SECRETARY OF THE UNITED STATES OF AMERICA | 2007-03-22 | — | — | US | disclosed |
| US-20060287520-A1 | Synthesis of salinosporamide A and analogues thereof | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2006-12-21 | — | — | US | disclosed |
| US-20050282787-A1 | Synthesis of tetracyclines and analogues thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2005-12-22 | — | — | US | disclosed |
| US-6747023-B1 | INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-06-08 | — | — | US | disclosed |
| EP-1104754-A1 | NOVEL SULFONYL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066851-A1 | Palladium-catalyzed carbon-carbon bond forming reactions | APEX1, PCNA, DNMT3A | HTR2A 4650/4885RAB9A 3319/4885IDO1 1593/4885 |
| US-20050282787-A1 | Synthesis of tetracyclines and analogues thereof | TET1, TET3, MYC | HTR2A 4066/4885RAB9A 3065/4885IDO1 1844/4885 |
| US-20240229026-A1 | CHIRAL CONTROL | RNGTT, POLI, NSUN3 | HTR2A 3340/4885RAB9A 4790/4885IDO1 1297/4885 |
| US-20150376201-A1 | CORTISTATIN ANALOGUES AND SYNTHESES THEREOF | CTTN, TEK, FLT1 | HTR2A 4246/4885RAB9A 968/4885IDO1 4569/4885 |
| US-10870651-B2 | Inhibitors of cyclin-dependent kinase 7 (CDK7) | CDK7, CDK3, CDK9 | HTR2A 3718/4885RAB9A 1269/4885IDO1 1527/4885 |
| US-12037355-B2 | Triterpene saponin analogues | LSS, NFATC1, PGGT1B | HTR2A 4655/4885RAB9A 3843/4885IDO1 579/4885 |
| US-20060287520-A1 | Synthesis of salinosporamide A and analogues thereof | PSMB5, ERG28, PSMB11 | HTR2A 2626/4885RAB9A 1592/4885IDO1 2476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.