Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4946065 | 0.80 | CRHBP (0.44) | CRHBPCRHR2CYP2C9CYP2D6CYP1A2 | |
| SCHEMBL283048 | 0.80 | RORC (0.35) | CRHBPCRHR2RORCCYP2C9PTPN5 | |
| SCHEMBL16182145 | 0.80 | RORC (0.35) | CRHBPCRHR2RORCCYP2C9PTPN5 | |
| SCHEMBL438674 | 0.79 | MAPK1 (0.39) | CRHBPCRHR2RORCCYP2C9CYP2D6 | |
| SCHEMBL438804 | 0.77 | RORC (0.35) | CRHBPCRHR2RORCCYP2C9PTPN5 | |
| SCHEMBL440108 | 0.75 | ALDH1A1 (0.35) | RORCCYP2C9PTPN5CYP2D6CYP1A2 | |
| SCHEMBL1758324 | 0.74 | CRHBP (0.48) | CRHBPCRHR2CYP2C9CYP2D6CYP1A2 | |
| SCHEMBL19881693 | 0.72 | TRPA1 (0.36) | TRPA1ALDH1A1TRPV1 | |
| SCHEMBL13776779 | 0.72 | CYP2A6 (0.42) | CRHBPCRHR2CYP2C9CYP2D6CYP1A2 | |
| SCHEMBL16202902 | 0.72 | TRPV1 (0.40) | CYP2C9PTPN5CYP2D6CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265689-B1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2018-06-20 | — | — | EP | disclosed |
| US-8927117-B2 | Materials for organic electroluminescence device | MERCK PATENT GMBH (DE) | 2015-01-06 | — | — | US | disclosed |
| US-8927117-B2 | Materials for organic electroluminescence device | MERCK PATENT GMBH (DE) | 2015-01-06 | — | — | US | disclosed |
| US-8927117-B2 | Materials for organic electroluminescence device | MERCK PATENT GMBH (DE) | 2015-01-06 | — | — | US | disclosed |
| CN-102007194-A | Novel materials for organic electroluminescent devices | MERCK PATENT GMBH | 2011-04-06 | — | — | CN | disclosed |
| US-20110037063-A1 | NOVEL MATERILS FOR ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2011-02-17 | — | — | US | disclosed |
| US-20110037063-A1 | NOVEL MATERILS FOR ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2011-02-17 | — | — | US | disclosed |
| US-20110037063-A1 | NOVEL MATERILS FOR ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2011-02-17 | — | — | US | disclosed |
| EP-2265689-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | Merck Patent GmbH (DE) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009127307-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2009-10-22 | — | — | WO | disclosed |
| WO-2009127307-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2009-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110037063-A1 | NOVEL MATERILS FOR ORGANIC ELECTROLUMINESCENCE DEVICE | L1CAM, EML4, SLC40A1 | CRHBP 2345/4885CRHR2 3092/4885RORC 3167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.