Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10796823 | 0.83 | TSHR (0.45) | PTGS2MAPTTDP1ALDH1A1KMT2A | |
| SCHEMBL4602487 | 0.83 | PTGS2 (0.36) | PTGS2MAPTNPSR1TDP1ALDH1A1 | |
| SCHEMBL12777347 | 0.81 | NPBWR1 (0.40) | KAT2BPTGS2MAPTTDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11086100 | 0.77 | LOXL2 (0.53) | LOXL2KAT2BCA9MAPTNPSR1 | |
| SCHEMBL31423774 | 0.75 | TDP1 (0.60) | LOXL2MAPTNPSR1TDP1ALDH1A1 | |
| SCHEMBL11079242 | 0.75 | TDP1 (0.60) | LOXL2MAPTNPSR1TDP1ALDH1A1 | |
| SCHEMBL30929373 | 0.75 | ALDH1A1 (0.57) | MAPTTDP1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL17341954 | 0.75 | ALDH5A1 (0.44) | PTGS2MAPTTDP1ALDH1A1KMT2A | |
| SCHEMBL6410654 | 0.75 | ALDH1A1 (0.57) | MAPTTDP1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL366120 | 0.74 | TSHR (0.60) | KAT2BPTGS2MAPTNPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403852-B1 | 2-AMINOBENZIMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INT (DE) | 2014-10-29 | — | — | EP | disclosed |