Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653035 | 0.85 | TSHR (0.60) | TSHRCYP3A4GPR35MEN1MAPT | |
| SCHEMBL3017185 | 0.83 | TSHR (0.62) | TSHRCYP3A4GPR35MEN1MAPT | |
| SCHEMBL18911952 | 0.81 | TSHR (0.41) | TSHRCYP3A4GPR35MEN1MAPT | |
| SCHEMBL6410654 | 0.79 | ALDH1A1 (0.57) | TSHRCYP3A4GPR35MAPTKMT2A | |
| SCHEMBL30929373 | 0.79 | ALDH1A1 (0.57) | TSHRCYP3A4GPR35MAPTKMT2A | |
| SCHEMBL17341954 | 0.79 | ALDH5A1 (0.44) | MEN1MAPTKMT2AALDH1A1PTGS2 | |
| SCHEMBL9686162 | 0.79 | PTGS2 (0.66) | MAPTKMT2ASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL366123 | 0.78 | MAPK1 (0.53) | TSHRNPSR1ALDH1A1POLB | |
| SCHEMBL14833771 | 0.78 | TDP1 (0.53) | MAPTKMT2AALDH1A1PTGS2TDP1 | |
| SCHEMBL11216418 | 0.78 | BACE1 (0.49) | TSHRGPR35MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117113-A | Polysubstituted carbazole, derivant and synthetic method thereof | 湘潭大学 | 2016-11-16 | — | — | CN | claimed |
| CN-103848830-B | A kind of simple and easy method of synthesis imidazo [1,2-α] pyridine derivate | 淮阴师范学院 | 2016-08-03 | — | — | CN | claimed |
| EP-2970176-B1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2023-10-25 | — | — | EP | disclosed |
| CN-115025073-A | Application of non-classical antibacterial activity of phenylalkene nitro compound as quorum sensing inhibitor | 海南大学 | 2022-09-09 | — | — | CN | disclosed |
| CN-111196778-B | Synthetic method of 3-ethylamino pyrrole compound | 郑州轻工业大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-112174952-B | Beta-carboline-oxazoline novel multifunctional ligand beta3Carox, its preparation and application | 南京农业大学 | 2022-03-29 | — | — | CN | disclosed |
| CN-112174953-B | Novel beta-carboline-oxazoline multifunctional ligand beta1Carox, its preparation and application | 南京农业大学 | 2022-03-29 | — | — | CN | disclosed |
| CN-109225339-B | Hierarchical assembly method and application of high-activity synergistic MOF catalyst | 合肥工业大学 | 2021-05-25 | — | — | CN | disclosed |
| CN-112174952-A | Beta-carboline-oxazoline novel multifunctional ligand beta3Carox, its preparation and application | 南京农业大学 | 2021-01-05 | — | — | CN | disclosed |
| CN-107573295-B | Molecules and intermediates having pesticidal utility, compositions and methods relating thereto | 美国陶氏益农公司 | 2020-12-15 | — | — | CN | disclosed |
| CN-111196778-A | Synthetic method of 3-ethylamino pyrrole compound | 郑州轻工业大学 | 2020-05-26 | — | — | CN | disclosed |
| WO-2014160031-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20140274688-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140274688-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140275524-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140275524-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140275047-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140275047-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2014-09-18 | — | — | US | disclosed |
| WO-2012009372-A2 | TRIAZOLIUM CARBENE CATALYSTS AND PROCESSES FOR ASYMMETRIC CARBON-CARBON BOND FORMATION | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-01-19 | — | — | WO | disclosed |
| EP-0181833-A1 | Substituted propane-phosphonous acid compounds | CIBA-GEIGY AG (CH) | 1986-05-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275524-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | ACHE, DDT, MLYCD | TSHR 2895/4885CYP3A4 795/4885GPR35 3775/4885 |
| US-20140275047-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | ACHE, DDT, MLYCD | TSHR 2895/4885CYP3A4 795/4885GPR35 3775/4885 |
| US-20140274688-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | ACHE, DDT, MLYCD | TSHR 2895/4885CYP3A4 795/4885GPR35 3775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.