Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 4/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.37 |
| ▸ | DNPEP | Q9ULA0 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288760 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TDP1ANPEPRNPEPDNPEP | |
| SCHEMBL22677513 | 0.80 | USP2 (0.31) | ALDH1A1TDP1CA1 | |
| SCHEMBL8338768 | 0.79 | MAOA (0.47) | ALDH1A1ANPEPRNPEPDNPEPCA1 | |
| SCHEMBL20085628 | 0.79 | PAOX (0.39) | ALDH1A1TDP1ANPEPRNPEPDNPEP | |
| SCHEMBL25159888 | 0.77 | ANPEP (0.35) | ALDH1A1ANPEPRNPEPDNPEPCA1 | |
| SCHEMBL5538723 | 0.77 | TET2 (0.39) | ANPEPRNPEPDNPEPSMN1; SMN2RAB9A | |
| SCHEMBL24508253 | 0.76 | RARB (0.34) | ALDH1A1SMN1; SMN2KISS1R | |
| SCHEMBL16213675 | 0.76 | LMNA (0.30) | LMNA | |
| SCHEMBL25453161 | 0.74 | ALDH1A1 (0.33) | ALDH1A1TDP1 | |
| SCHEMBL21335952 | 0.74 | GSR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230292741-A1 | NOVEL SUPERCOOLING METHODS FOR PRESERVATION OF BIOLOGICAL SAMPLES | X-THERMA, INC. (US) | 2023-09-21 | — | — | US | disclosed |
| US-20180111905-A1 | N2-(2-METHOXYPHENYL)PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR CANCER PREVENTION OR TREATMENT CONTAINING SAME AS ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2018-04-26 | — | — | US | disclosed |
| US-20150031743-A1 | CELL TRANSFECTING FORMULATIONS OF SMALL INTERFERING RNA, RELATED COMPOSITIONS AND METHODS OF MAKING AND USE | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2015-01-29 | — | — | US | disclosed |
| US-8772255-B2 | Cell transfecting formulations of small interfering RNA related compositions and methods of making and use | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2014-07-08 | — | — | US | disclosed |
| US-20090143322-A1 | CELL TRANSFECTING FORMULATIONS OF SMALL INTERFERING RNA RELATED COMPOSITIONS AND METHODS OF MAKING AND USE | CHIRON CORPORATION (US) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180111905-A1 | N2-(2-METHOXYPHENYL)PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR CANCER PREVENTION OR TREATMENT CONTAINING SAME AS ACTIVE INGREDIENT | ALK, NPM1, EML4 | ALDH1A1 1803/4885TDP1 1272/4885ANPEP 120/4885 |
| US-20090143322-A1 | CELL TRANSFECTING FORMULATIONS OF SMALL INTERFERING RNA RELATED COMPOSITIONS AND METHODS OF MAKING AND USE | SNRPE, SNRPA, PHAX | ALDH1A1 4470/4885TDP1 2572/4885ANPEP 2842/4885 |
| US-20150031743-A1 | CELL TRANSFECTING FORMULATIONS OF SMALL INTERFERING RNA, RELATED COMPOSITIONS AND METHODS OF MAKING AND USE | SNRPE, PHAX, SNRPA | ALDH1A1 4443/4885TDP1 2518/4885ANPEP 2876/4885 |
| US-20230292741-A1 | NOVEL SUPERCOOLING METHODS FOR PRESERVATION OF BIOLOGICAL SAMPLES | PPIG, AQP3, AQP1 | ALDH1A1 4823/4885TDP1 888/4885ANPEP 1611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.