Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13287470 | 0.82 | RAB9A (0.41) | RAB9AL3MBTL1KMT2ANCOA1SMN1; SMN2 | |
| SCHEMBL13764517 | 0.81 | LMNA (0.39) | L3MBTL1KMT2ASMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL26196840 | 0.79 | ALPG (0.48) | KMT2ALMNAALDH1A1POLBFPR2 | |
| SCHEMBL17865370 | 0.79 | KCNH2 (0.41) | KMT2ASMN1; SMN2LMNAMEN1ALDH1A1 | |
| SCHEMBL20425451 | 0.77 | KCNH2 (0.42) | FPR2 | |
| SCHEMBL11295344 | 0.76 | KCNH2 (0.42) | KMT2ALMNAALDH1A1POLB | |
| SCHEMBL10292434 | 0.76 | FPR2 (0.45) | RAB9AL3MBTL1KMT2ANCOA1SMN1; SMN2 | |
| SCHEMBL23053790 | 0.76 | KCNH2 (0.33) | KMT2ALMNAMEN1ALDH1A1POLB | |
| Bromide SCHEMBL18979889 | 0.76 | KCNH2 (0.41) | FPR2 | |
| SCHEMBL28699417 | 0.75 | ALDH1A1 (0.39) | KMT2ASMN1; SMN2LMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877970-B2 | Inhibitors of carbonic anhydrase IX | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2014-11-04 | — | — | US | disclosed |