Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16235020 | 0.83 | KMT2A (0.34) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL16235562 | 0.83 | MEN1 (0.34) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL16235078 | 0.74 | POLB (0.34) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL16235054 | 0.70 | HTT (0.31) | MAPTHTT | |
| SCHEMBL16235789 | 0.66 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTHTT | |
| SCHEMBL16235685 | 0.66 | SMN1; SMN2 (0.49) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL16235221 | 0.66 | CYP17A1 (0.36) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL16234970 | 0.62 | ALDH1A1 (0.31) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL16235348 | 0.59 | CCR4 (0.35) | — | |
| SCHEMBL29131000 | 0.58 | MAPT (0.36) | KMT2AMEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925743-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | Active Biotech AB (SE) | 2015-10-07 | — | — | EP | disclosed |
| WO-2014184234-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | ACTIVE BIOTECH AB (SE) | 2014-11-20 | — | — | WO | disclosed |