Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | FGB | P02675 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27903386 | 0.80 | LMNA (0.44) | KMT2AMEN1CYP1A2USP2CYP3A4 | |
| SCHEMBL28164979 | 0.78 | MTNR1A (0.37) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28164991 | 0.78 | APP (0.38) | KMT2AMEN1CYP1A2USP2CASP1 | |
| SCHEMBL16235881 | 0.77 | ALDH1A1 (0.41) | KMT2AMEN1CYP1A2USP2ESR1 | |
| SCHEMBL23956107 | 0.76 | ALDH1A1 (0.56) | CYP1A2ALDH1A1POLBKDM4ETSHR | |
| SCHEMBL28165404 | 0.76 | MCL1 (0.41) | KMT2AALDH1A1MAPTMTNR1AMTNR1B | |
| SCHEMBL6750659 | 0.75 | ALDH1A1 (0.63) | CYP1A2ALDH1A1POLBMTNR1AMTNR1B | |
| SCHEMBL27990355 | 0.73 | L3MBTL1 (0.59) | KMT2AMEN1CYP1A2ALDH1A1POLB | |
| SCHEMBL28165429 | 0.72 | CNR2 (0.47) | KMT2AMEN1CYP1A2CASP1ALDH1A1 | |
| SCHEMBL8043623 | 0.72 | CCR2 (0.54) | KMT2ACYP1A2ESR1CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997028-A1 | AZA-OXO-INDOLES FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | F.HOFFMANN-LA ROCHE AG (CH) | 2016-03-23 | — | — | EP | disclosed |
| WO-2014184163-A1 | AZA-OXO-INDOLES FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2014-11-20 | — | — | WO | disclosed |