Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27903386 | 0.82 | LMNA (0.44) | MTNR1AMTNR1BKMT2AMAPTCNR2 | |
| SCHEMBL28164979 | 0.81 | MTNR1A (0.37) | MTNR1AMTNR1BKMT2AMAPTTP53 | |
| SCHEMBL28164991 | 0.81 | APP (0.38) | MTNR1AMTNR1BKMT2AMAPTBACE1 | |
| SCHEMBL28165429 | 0.81 | CNR2 (0.47) | KMT2AMAPTCNR2TP53KDM4E | |
| SCHEMBL23956107 | 0.78 | ALDH1A1 (0.56) | KDM4ECRHBPCRHR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8043623 | 0.78 | CCR2 (0.54) | KMT2ANOD2NOD1MAPTTP53 | |
| SCHEMBL16236089 | 0.76 | KMT2A (0.39) | MCL1MTNR1AMTNR1BKMT2AMAPT | |
| SCHEMBL28443020 | 0.73 | CNR2 (0.39) | MCL1SLC9A1CNR2TP53KDM4E | |
| SCHEMBL9040161 | 0.73 | ALDH1A1 (0.61) | MCL1MTNR1AMTNR1BKMT2ABACE1 | |
| SCHEMBL4912683 | 0.72 | KMT2A (0.50) | MCL1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928121-A | The high efficiency preparation method of 3- substitution-benzo five-membered heterocycle -2- carbonyls | 暨南大学 | 2017-07-07 | — | — | CN | disclosed |