Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 4/20 | 0.50 |
| ▸ | NOS3 | P29474 | 3/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7008513 | 0.78 | NOS2 (0.52) | NOS2NOS3SKP2MAPK1NFKB1 | |
| SCHEMBL28129531 | 0.77 | NOS2 (0.50) | NOS2NOS3SKP2MAPK1NFKB1 | |
| SCHEMBL8713672 | 0.77 | NOS2 (0.82) | NOS2NOS3SKP2TLR8TLR7 | |
| SCHEMBL28135505 | 0.72 | TYR (0.42) | NOS2MAPK1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL25027836 | 0.72 | NOS2 (0.45) | NOS2NOS3SKP2MAPK1NFKB1 | |
| SCHEMBL27839140 | 0.71 | NOS2 (0.43) | NOS2NOS3SKP2MAPK1NFKB1 | |
| SCHEMBL21806238 | 0.70 | NOS2 (0.77) | NOS2NOS3RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28052887 | 0.70 | NOS2 (0.47) | NOS2NOS3NPC1RAB9AL3MBTL1 | |
| SCHEMBL27672334 | 0.70 | NOS2 (0.47) | NOS2NOS3NPC1RAB9AL3MBTL1 | |
| SCHEMBL26177037 | 0.69 | NOS2 (0.66) | NOS2NOS3ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10211414-B2 | Phosphorescent tetradentate metal complexes having modified emission spectra | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2019-02-19 | — | — | US | disclosed |
| US-9899614-B2 | Phosphorescent tetradentate metal complexes having modified emission spectra | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-02-20 | — | — | US | disclosed |
| US-20170331056-A1 | PHOSPHORESCENT TETRADENTATE METAL COMPLEXES HAVING MODIFIED EMISSION SPECTRA | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2017-11-16 | — | — | US | disclosed |
| US-9673409-B2 | Phosphorescent tetradentate metal complexes having modified emission spectra | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2017-06-06 | — | — | US | disclosed |
| US-20160285015-A1 | PHOSPHORESCENT TETRADENTATE METAL COMPLEXES HAVING MODIFIED EMISSION SPECTRA | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2016-09-29 | — | — | US | disclosed |
| WO-2015027060-A1 | PHOSPHORESCENT TETRADENTATE METAL COMPLEXES HAVING MODIFIED EMISSION SPECTRA | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2015-02-26 | — | — | WO | disclosed |
| US-20140364605-A1 | PHOSPHORESCENT TETRADENTATE METAL COMPLEXES HAVING MODIFIED EMISSION SPECTRA | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2014-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170331056-A1 | PHOSPHORESCENT TETRADENTATE METAL COMPLEXES HAVING MODIFIED EMISSION SPECTRA | AP2S1, PICALM, TRPC3 | NOS2 4685/4885NOS3 4472/4885SKP2 1115/4885 |
| US-10211414-B2 | Phosphorescent tetradentate metal complexes having modified emission spectra | AP2S1, PICALM, TRPC3 | NOS2 4685/4885NOS3 4472/4885SKP2 1115/4885 |
| US-20160285015-A1 | PHOSPHORESCENT TETRADENTATE METAL COMPLEXES HAVING MODIFIED EMISSION SPECTRA | OCIAD1, OCIAD2, OSGEP | NOS2 3688/4885NOS3 3536/4885SKP2 2657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.