Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP51A1 | Q16850 | 3/20 | 0.40 |
| ▸ | SMO | Q99835 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | SFN | P31947 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18074915 | 0.79 | CYP51A1 (0.45) | CA1CA2CA5ACA9CA5B | |
| SCHEMBL22683759 | 0.76 | CYP51A1 (0.42) | CA1CA2CA5ACA9CA5B | |
| SCHEMBL23157402 | 0.76 | IDO1 (0.48) | CA1CA2CA5ACA9CA5B | |
| SCHEMBL16288086 | 0.75 | CA1 (0.41) | CA1CA2CA5ACA9CA5B | |
| SCHEMBL29101 | 0.73 | MEN1 (0.45) | TSHR | |
| SCHEMBL29100 | 0.73 | MEN1 (0.45) | TSHR | |
| SCHEMBL26048600 | 0.73 | PTGS2 (0.41) | CA1CA2CA5ACA9CA5B | |
| SCHEMBL16242461 | 0.72 | CA1 (0.48) | CA1CA2CA5ACA9CA5B | |
| SCHEMBL15083519 | 0.72 | CA1 (0.42) | CA1CA2CA5ACA9CA5B | |
| SCHEMBL23157115 | 0.72 | TP53 (0.42) | CA1CA2CA5ACA9CA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240197924-A1 | CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2024-06-20 | — | — | US | claimed |
| WO-2020022892-A1 | TUBULYSIN DERIVATIVES AND METHODS FOR PREPARING THE SAME | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-01-30 | — | — | WO | claimed |
| US-20240166689-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-05-23 | — | — | US | disclosed |
| US-11891457-B2 | Peptide-compound cyclization method | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-02-06 | — | — | US | disclosed |
| US-11241507-B2 | Near-infrared chemiluminescent probes for in-vivo imaging | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2022-02-08 | — | — | US | disclosed |
| EP-2813512-B1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2021-03-31 | — | — | EP | disclosed |
| US-20210061860-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2021-03-04 | — | — | US | disclosed |
| CN-111936627-A | Asparaginase activity polypeptides, expression cassettes, expression vectors, host cells, compositions, methods, cancer prevention or treatment uses | 奥斯瓦道·克鲁兹基金会 | 2020-11-13 | — | — | CN | disclosed |
| US-20200131669-A1 | CYCLIC PEPTIDE COMPOUND HAVING HIGH MEMBRANE PERMEABILITY, AND LIBRARY CONTAINING SAME | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2020-04-30 | — | — | US | disclosed |
| EP-3636807-A1 | CYCLIC PEPTIDE COMPOUND HAVING HIGH MEMBRANE PERMEABILITY, AND LIBRARY CONTAINING SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 2020-04-15 | — | — | EP | disclosed |
| US-20200040372-A1 | METHOD FOR SYNTHESIZING PEPTIDES IN CELL-FREE TRANSLATION SYSTEM | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2020-02-06 | — | — | US | disclosed |
| EP-3041852-B1 | SEPARATION MATERIAL COMPRISING PHOSPHORYL CHOLINE DERIVATIVES | PENTRACOR GMBH (DE) | 2017-05-31 | — | — | EP | disclosed |
| US-20170120163-A1 | SEPARATION MATERIAL COMPRISING PHOSPHORYL CHOLINE DERIVATIVES | PENTRACOR GMBH (DE) | 2017-05-04 | — | — | US | disclosed |
| US-20160311858-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2016-10-27 | — | — | US | disclosed |
| US-9409952-B2 | Peptide-compound cyclization method | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2016-08-09 | — | — | US | disclosed |
| EP-3041852-A1 | SEPARATION MATERIAL COMPRISING PHOSPHORYL CHOLINE DERIVATIVES | Pentracor GmbH (DE) | 2016-07-13 | — | — | EP | disclosed |
| EP-2957563-A1 | Separation material comprising phosphoryl choline derivatives | Pentracor GmbH (DE) | 2015-12-23 | — | — | EP | disclosed |
| WO-2015193504-A1 | SEPARATION MATERIAL COMPRISING PHOSPHORYL CHOLINE DERIVATIVES | PENTRACOR GMBH (DE) | 2015-12-23 | — | — | WO | disclosed |
| US-20150080549-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2015-03-19 | — | — | US | disclosed |
| EP-2813512-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | Chugai Seiyaku Kabushiki Kaisha (JP) | 2014-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170120163-A1 | SEPARATION MATERIAL COMPRISING PHOSPHORYL CHOLINE DERIVATIVES | CHKA, PHOSPHO1, C3AR1 | CA1 1282/4885CA2 1814/4885CA5A 3843/4885 |
| US-11891457-B2 | Peptide-compound cyclization method | VIP, NGLY1, GLP1R | CA1 1024/4885CA2 2242/4885CA5A 2761/4885 |
| US-20210061860-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | VIP, NGLY1, GLP1R | CA1 1024/4885CA2 2242/4885CA5A 2761/4885 |
| US-20200040372-A1 | METHOD FOR SYNTHESIZING PEPTIDES IN CELL-FREE TRANSLATION SYSTEM | AARS1, NSUN3, RNGTT | CA1 4578/4885CA2 4555/4885CA5A 3583/4885 |
| US-20240166689-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | VIP, NGLY1, GLP1R | CA1 1024/4885CA2 2242/4885CA5A 2761/4885 |
| US-20200131669-A1 | CYCLIC PEPTIDE COMPOUND HAVING HIGH MEMBRANE PERMEABILITY, AND LIBRARY CONTAINING SAME | VIP, SLC7A1, TRPV1 | CA1 1979/4885CA2 1042/4885CA5A 1843/4885 |
| US-20160311858-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | VIP, NGLY1, GLP1R | CA1 1024/4885CA2 2242/4885CA5A 2761/4885 |
| US-11241507-B2 | Near-infrared chemiluminescent probes for in-vivo imaging | DHPS, DOHH, DAZAP1 | CA1 45/4885CA2 1474/4885CA5A 475/4885 |
| US-20150080549-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | VIP, NGLY1, GLP1R | CA1 1024/4885CA2 2242/4885CA5A 2761/4885 |
| US-20240197924-A1 | CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING | DAXX, CDYL, AOC1 | CA1 471/4885CA2 1682/4885CA5A 352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.