Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPEPPS | P55786 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4A | O75164 | 2/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28890119 | 0.85 | PKM (0.40) | NPEPPSKDM4EHSD17B10KMT2AALDH1A1 | |
| SCHEMBL4639335 | 0.81 | GPR119 (0.43) | NPEPPSKDM4EHSD17B10ALDH1A1CASP1 | |
| SCHEMBL31097820 | 0.78 | P4HA1 (0.46) | HSD17B10ALDH1A1LMNANAPRTP4HTM | |
| SCHEMBL23053142 | 0.74 | ALDH1A1 (0.40) | NPEPPSKDM4EHSD17B10KMT2AALDH1A1 | |
| SCHEMBL7939397 | 0.74 | ALDH1A1 (0.36) | NPEPPSKDM4EHSD17B10KMT2AALDH1A1 | |
| SCHEMBL10649891 | 0.66 | ALDH1A1 (0.45) | KDM4EHSD17B10KMT2AALDH1A1CASP1 | |
| SCHEMBL31228434 | 0.65 | HSD11B1 (0.49) | LMNANAPRTP4HTML3MBTL1RIPK1 | |
| SCHEMBL1740411 | 0.65 | HSD11B1 (0.49) | LMNANAPRTP4HTML3MBTL1RIPK1 | |
| SCHEMBL12915391 | 0.65 | KDM4E (0.46) | KDM4EHSD17B10KMT2AALDH1A1LMNA | |
| SCHEMBL23280559 | 0.63 | KDM4E (0.44) | KDM4EHSD17B10KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444312-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107552-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| US-9073856-B2 | Phenyl methanesulfonamide derivatives useful as MGAT-2 inhibitors | ELI LILLY AND COMPANY (US) | 2015-07-07 | — | — | US | disclosed |
| US-20140371269-A1 | PHENYL METHANESULFONAMIDE DERIVATIVES USEFUL AS MGAT-2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2014-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371269-A1 | PHENYL METHANESULFONAMIDE DERIVATIVES USEFUL AS MGAT-2 INHIBITORS | MGST1, MGAT1, MGAT2 | NPEPPS 1070/4885KDM4E 2664/4885HSD17B10 231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.