Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | QDPR | P09417 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12353792 | 0.74 | MAOA (0.52) | MAOBHPGDRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12354084 | 0.70 | HPGD (0.52) | MAOBHPGDRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16306693 | 0.70 | RAB9A (0.49) | MAOBHPGDRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28222855 | 0.68 | SCN9A (0.48) | HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL23290629 | 0.67 | QDPR (0.38) | MAOBQDPRHTR2CSIGMAR1 | |
| Hydrochloric Acid SCHEMBL23290416 | 0.67 | QDPR (0.38) | MAOBQDPRHTR2CSIGMAR1 | |
| SCHEMBL17109235 | 0.66 | RBP4 (0.43) | HPGDRAB9ASMN1; SMN2NAMPTALDH1A1 | |
| SCHEMBL14718387 | 0.65 | QDPR (0.36) | QDPRSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL23290146 | 0.64 | KHK (0.38) | MAOBRAB9AQDPRNPC1HTR2C | |
| SCHEMBL10198640 | 0.64 | QDPR (0.57) | QDPRHTR2CSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014199933-A1 | BICYCLIC NITROGEN-CONTAINING AROMATIC HETEROCYCLIC AMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2014-12-18 | — | — | WO | disclosed |