Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.49 |
| ▸ | HTR2B | P41595 | 3/20 | 0.49 |
| ▸ | SRD5A1 | P18405 | 6/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10671459 | 0.75 | HTR2C (0.57) | HTR2CHTR2BSRD5A1OPRM1CHRM2 | |
| SCHEMBL6946528 | 0.71 | SRD5A1 (0.52) | HTR2CHTR2BSRD5A1OPRM1CHRM2 | |
| SCHEMBL3723794 | 0.71 | OPRM1 (0.65) | HTR2CHTR2BOPRM1TSHRMEN1 | |
| SCHEMBL12638317 | 0.71 | HTR2C (0.71) | HTR2CHTR2BSRD5A1OPRM1DRD3 | |
| SCHEMBL10652419 | 0.71 | HTR2C (0.71) | HTR2CHTR2BSRD5A1OPRM1DRD3 | |
| SCHEMBL31091227 | 0.70 | NOTUM (0.56) | HTR2CHTR2BSRD5A1OPRM1CHRM2 | |
| SCHEMBL10653852 | 0.69 | HTR2C (0.69) | HTR2CHTR2BSRD5A1OPRM1DRD3 | |
| SCHEMBL16307929 | 0.69 | SLC18A3 (0.49) | TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL11262644 | 0.68 | MTNR1A (0.46) | HTR2CHTR2BSRD5A1OPRM1CHRM2 | |
| SCHEMBL16307942 | 0.67 | FAAH (0.44) | HTR2CHTR2BOPRM1HTR1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938253-B2 | Catalysts for efficient Z-selective metathesis | TRUSTEES OF BOSTON COLLEGE (US) | 2018-04-10 | — | — | US | disclosed |
| US-9938253-B2 | Catalysts for efficient Z-selective metathesis | TRUSTEES OF BOSTON COLLEGE (US) | 2018-04-10 | — | — | US | disclosed |
| US-20140371454-A1 | CATALYSTS FOR EFFICIENT Z-SELECTIVE METATHESIS | TRUSTEES OF BOSTON COLLEGE | 2014-12-18 | — | — | US | disclosed |
| US-20140371454-A1 | CATALYSTS FOR EFFICIENT Z-SELECTIVE METATHESIS | TRUSTEES OF BOSTON COLLEGE | 2014-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371454-A1 | CATALYSTS FOR EFFICIENT Z-SELECTIVE METATHESIS | ADH5, ADH1A, ADH1C | HTR2C 1790/4885HTR2B 2473/4885SRD5A1 272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.