Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16319842 | 0.90 | BMPR1B (0.45) | HPGDLMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL16320026 | 0.82 | HCAR3 (0.48) | HPGDLMNANPC1RAB9ACYP1A2 | |
| SCHEMBL16320397 | 0.81 | FAAH (0.44) | EPHX2 | |
| SCHEMBL16320332 | 0.80 | RAB9A (0.52) | HPGDALDH1A1LMNAL3MBTL1NPC1 | |
| SCHEMBL3514598 | 0.79 | HPGD (0.45) | HPGDALDH1A1EPHX2GAATSHR | |
| SCHEMBL16319748 | 0.77 | FYN (0.43) | ALDH1A1LMNAGAANPC1RAB9A | |
| SCHEMBL3515520 | 0.77 | HRH3 (0.47) | EPHX2 | |
| SCHEMBL3513460 | 0.76 | L3MBTL3 (0.51) | HPGDLMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL8170956 | 0.75 | F2 (0.40) | GAA | |
| SCHEMBL16319440 | 0.74 | SMN1; SMN2 (0.48) | HPGDALDH1A1LMNAMAPK1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2544684-B1 | 4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES USEFUL AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-1 (DPP-1) | JANSSEN PHARMACEUTICA NV (BE) | 2014-12-24 | — | — | EP | disclosed |