Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL20742739 | 0.83 | MAPT (0.33) | MAPT | |
| SCHEMBL2294957 | 0.83 | MAPT (0.33) | MAPT | |
| Phenazine SCHEMBL2923781 | 0.67 | MAPT (0.65) | TSHRSMN1; SMN2KDM4EMAPTHPGD | |
| Phenazine SCHEMBL8564741 | 0.67 | MAPT (0.65) | TSHRSMN1; SMN2KDM4EMAPTHPGD | |
| Phenazine SCHEMBL28835271 | 0.65 | MAPT (0.61) | TSHRSMN1; SMN2KDM4EMAPTHPGD | |
| Naphthalene SCHEMBL672294 | 0.63 | ALOX12 (0.57) | TSHRSMN1; SMN2KDM4EMAPTHPGD | |
| Naphthalene SCHEMBL28674544 | 0.63 | ALOX12 (0.57) | TSHRSMN1; SMN2KDM4EMAPTHPGD | |
| Naphthalene SCHEMBL29361795 | 0.63 | ALOX12 (0.57) | TSHRSMN1; SMN2KDM4EMAPTHPGD | |
| Sulfuric Acid SCHEMBL3380495 | 0.63 | MAPT (0.59) | TSHRSMN1; SMN2KDM4EMAPTHPGD | |
| Naphthalene SCHEMBL5574575 | 0.63 | ALOX12 (0.57) | TSHRSMN1; SMN2KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9518030-B2 | Purification of aryltriazoles | BELTER RANDOLPH K (US) | 2016-12-13 | — | — | US | disclosed |
| US-20160090367-A1 | Purification of Aryltriazoles | BELTER RANDOLPH K (US) | 2016-03-31 | — | — | US | disclosed |
| US-9242942-B2 | Purification of aryltriazoles | BELTER RANDOLPH K (US) | 2016-01-26 | — | — | US | disclosed |
| US-20150005508-A1 | Purification of Aryltriazoles | BELTER RANDOLPH KENNETH (US) | 2015-01-01 | — | — | US | disclosed |