Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21597737 | 0.86 | — | — | |
| SCHEMBL4423855 | 0.82 | NOS3 (0.39) | ADORA2BPTGS1L3MBTL1ADORA2A | |
| SCHEMBL6229727 | 0.77 | ADORA2B (0.33) | ADORA2B | |
| SCHEMBL26860530 | 0.77 | ADORA2B (0.30) | ADORA2B | |
| SCHEMBL15100969 | 0.76 | BAZ2B (0.37) | ADORA2BPTGS1PTGS2TDP1L3MBTL1 | |
| SCHEMBL12203385 | 0.76 | ALDH1A1 (0.33) | TDP1L3MBTL1 | |
| SCHEMBL13734950 | 0.76 | CYP11B1 (0.30) | PTGS2 | |
| SCHEMBL4279839 | 0.75 | IRAK4 (0.30) | — | |
| SCHEMBL1364221 | 0.74 | — | — | |
| SCHEMBL20813280 | 0.74 | GRIN2A (0.34) | PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12410161-B2 | Tetrahydrobenzo-quinoline sulfonamides derivative compounds | UCB Biopharma SRL (BE) | 2025-09-09 | — | — | US | disclosed |
| US-12018021-B2 | Thiophene derivatives for the treatment of disorders caused by IgE | UCB Biopharma SRL (BE) | 2024-06-25 | — | — | US | disclosed |
| US-12018021-B2 | Thiophene derivatives for the treatment of disorders caused by IgE | UCB Biopharma SRL (BE) | 2024-06-25 | — | — | US | disclosed |
| CN-111187215-B | Fluorine-containing pyrazole amide derivative, preparation method and application thereof | 西北农林科技大学 | 2023-02-24 | — | — | CN | disclosed |
| US-20230051300-A1 | TETRAHYDROBENZO-QUINOLINE SULFONAMIDES DERIVATIVE COMPOUNDS | UCB Biopharma SRL (BE) | 2023-02-16 | — | — | US | disclosed |
| US-20220332709-A1 | Thiophene derivatives for the treatment of disorders caused by IgE | UCB Biopharma SRL (BE) | 2022-10-20 | — | — | US | disclosed |
| CN-114845777-A | Tetrahydrobenzo-quinoline sulfonamide derivative compounds | UCB生物制药有限责任公司 | 2022-08-02 | — | — | CN | disclosed |
| WO-2021130262-A1 | TETRAHYDROBENZO-QUINOLINE SULFONAMIDES DERIVATIVE COMPOUNDS | UCB Biopharma SRL (BE) | 2021-07-01 | — | — | WO | disclosed |
| EP-3810606-A1 | THIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS CAUSED BY IGE | UCB Biopharma SRL (BE) | 2021-04-28 | — | — | EP | disclosed |
| CN-112566910-A | Thiophene derivatives for the treatment of IgE induced diseases | UCB生物制药有限责任公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-111187215-A | Fluorine-containing pyrazole amide derivative, preparation method and application thereof | 西北农林科技大学 | 2020-05-22 | — | — | CN | disclosed |
| WO-2019243550-A1 | THIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS CAUSED BY IGE | UCB Biopharma SRL (BE) | 2019-12-26 | — | — | WO | disclosed |
| EP-3013821-B1 | PIPERIDINECARBOXYLIC ACID DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2018-03-14 | — | — | EP | disclosed |
| US-9717243-B2 | Piperidinecarboxylic acid derivatives as fungicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-08-01 | — | — | US | disclosed |
| US-20160135461-A1 | PIPERIDINECARBOXYLIC ACID DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-05-19 | — | — | US | disclosed |
| EP-3013821-A1 | PIPERIDINECARBOXYLIC ACID DERIVATIVES AS FUNGICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2016-05-04 | — | — | EP | disclosed |
| WO-2014206896-A1 | PIPERIDINECARBOXYLIC ACID DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2014-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230051300-A1 | TETRAHYDROBENZO-QUINOLINE SULFONAMIDES DERIVATIVE COMPOUNDS | HRH4, FCER2, HRH2 | ADORA2B 1608/4885PTGS1 484/4885PTGS2 210/4885 |
| US-12410161-B2 | Tetrahydrobenzo-quinoline sulfonamides derivative compounds | HRH4, FCER2, HRH2 | ADORA2B 1608/4885PTGS1 484/4885PTGS2 210/4885 |
| US-20220332709-A1 | Thiophene derivatives for the treatment of disorders caused by IgE | TSLP, CYSLTR1, CYSLTR2 | ADORA2B 2628/4885PTGS1 4/4885PTGS2 57/4885 |
| US-20160135461-A1 | PIPERIDINECARBOXYLIC ACID DERIVATIVES AS FUNGICIDES | CYP1A1, PRXL2A, Q6ZSR9 | ADORA2B 1371/4885PTGS1 128/4885PTGS2 711/4885 |
| US-12018021-B2 | Thiophene derivatives for the treatment of disorders caused by IgE | TSLP, CYSLTR1, CYSLTR2 | ADORA2B 2628/4885PTGS1 4/4885PTGS2 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.