Sugi Predict

Sugi Predict / Compounds / SCHEMBL1635362

SCHEMBL1635362

SCHEMBL1635362

C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC(I)[C@]4(C)[C@H]3C[C@H](O)[C@]12C

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPBAR1 Q8TDU6 10/20 0.71
▸ NR1H4 Q96RI1 3/20 0.71
▸ PDE3A Q14432 2/20 0.71
▸ TBXA2R P21731 1/20 0.71
▸ SLC10A2 Q12908 1/20 0.71
▸ MAPT P10636 3/20 0.57
▸ MAPK1 P28482 3/20 0.57
▸ LMNA P02545 3/20 0.57
▸ USP2 O75604 2/20 0.57
▸ MEN1 O00255 1/20 0.57
▸ KMT2A Q03164 1/20 0.57
▸ CYP3A4 P08684 2/20 0.56
▸ CASP7 P55210 3/20 0.56
▸ TP53 P04637 2/20 0.56
▸ HSD17B10 Q99714 2/20 0.56
▸ BLM P54132 2/20 0.56
▸ TDP1 Q9NUW8 2/20 0.56
▸ MDM4 O15151 1/20 0.56
▸ HSPD1 P10809 1/20 0.56
▸ VDR P11473 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1654288 0.92 GPBAR1 (0.76) GPBAR1NR1H4PDE3ATBXA2RSLC10A2
SCHEMBL21631677 0.92 GPBAR1 (0.76) GPBAR1NR1H4PDE3ATBXA2RSLC10A2
SCHEMBL7756845 0.92 GPBAR1 (0.76) GPBAR1NR1H4PDE3ATBXA2RSLC10A2
SCHEMBL21594795 0.92 GPBAR1 (0.76) GPBAR1NR1H4PDE3ATBXA2RSLC10A2
SCHEMBL3447484 0.92 GPBAR1 (0.76) GPBAR1NR1H4PDE3ATBXA2RSLC10A2
SCHEMBL7996290 0.89 GPBAR1 (0.72) GPBAR1NR1H4PDE3ATBXA2RSLC10A2
SCHEMBL4281815 0.87 GPBAR1 (0.69) GPBAR1NR1H4PDE3ATBXA2RSLC10A2
SCHEMBL4433404 0.86 GPBAR1 (0.68) GPBAR1NR1H4PDE3ATBXA2RSLC10A2
SCHEMBL1492140 0.85 GPBAR1 (0.66) GPBAR1NR1H4PDE3ATBXA2RSLC10A2
SCHEMBL8669402 0.85 GPBAR1 (0.66) GPBAR1NR1H4PDE3ATBXA2RSLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4316471-A1 ORAL NANOPARTICLES FOR BIOACTIVE COMPOUND, AND METHOD OF PREPARING SAME SNJ Pharma Inc (US) 2024-02-07 — — EP claimed
EP-3750531-A1 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF Amylyx Pharmaceuticals Inc. (US) 2020-12-16 — — EP claimed
US-20200230156-A1 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF Amylyx Pharmaceuticals Inc. 2020-07-23 — — US claimed
CN-110787169-A Compositions for improving cell viability and methods of using the same 艾米利克斯制药公司 2020-02-14 — — CN claimed
US-20190255072-A1 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF Amylyx Pharmaceuticals Inc. 2019-08-22 — — US claimed
EP-2978419-A1 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF Amylyx Pharmaceuticals Inc. (US) 2016-02-03 — — EP claimed
WO-2014158547-A1 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF Amylyx Pharmaceuticals Inc. (US) 2014-10-02 — — WO claimed
US-20140288030-A1 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF Amylyx Pharmaceuticals Inc. (US) 2014-09-25 — — US claimed
JP-4790123-B2 — — 2011-10-12 — — JP claimed
US-7932243-B2 Bile preparations for gastrointestinal disorders YOO SEO HONG 2011-04-26 — — US claimed
US-20060051319-A1 Neuroprotective effect of solubilized UDCA in focal ischemic model YOO SEO H 2006-03-09 — — US claimed
US-20050158408-A1 Dried forms of aqueous solubilized bile acid dosage formulation: preparation and uses thereof YOO SEO H (US) 2005-07-21 — — US claimed
EP-1113785-B1 CLEAR AQUEOUS SOLUTIONS OF BILE ACIDS YOO SEO HONG (US) 2005-04-13 — — EP claimed
US-20030186933-A1 Preparation of aqueous clear solution dosage forms with bile acids YOO SEO HONG (US) 2003-10-02 — — US claimed
EP-1255566-A2 PREPARATION OF AQUEOUS CLEAR SOLUTION DOSAGE FORMS WITH BILE ACIDS Yoo, Seo Hong (US) 2002-11-13 — — EP claimed
US-20020031558-A1 Preparation of aqueous clear solution dosage forms with bile acids YOO SEO HONG (US) 2002-03-14 — — US claimed
WO-2001056547-A2 PREPARATION OF AQUEOUS CLEAR SOLUTION DOSAGE FORMS WITH BILE ACIDS YOO SEO HONG (US) 2001-08-09 — — WO claimed
EP-1113785-A2 PREPARATION OF AQUEOUS CLEAR SOLUTION DOSAGE FORMS WITH BILE ACIDS Yoo, Seo Hong (US) 2001-07-11 — — EP claimed
US-6251428-B1 ADJUVANT, CARRIER YOO SEO HONG (US) 2001-06-26 — — US claimed
WO-2000004875-A2 PREPARATION OF AQUEOUS CLEAR SOLUTION DOSAGE FORMS WITH BILE ACIDS YOO SEO HONG (US) 2000-02-03 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200230156-A1 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF HSPA9, CYP27A1, TUFM GPBAR1 133/4885NR1H4 145/4885PDE3A 2885/4885
US-20030186933-A1 Preparation of aqueous clear solution dosage forms with bile acids SLC10A2, ABCB11, SLC10A1 GPBAR1 36/4885NR1H4 4/4885PDE3A 1090/4885
US-20190255072-A1 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF HSPA9, CYP27A1, TUFM GPBAR1 133/4885NR1H4 145/4885PDE3A 2885/4885
US-20140288030-A1 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF HSPA9, CYP27A1, TUFM GPBAR1 133/4885NR1H4 145/4885PDE3A 2885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.