SCHEMBL16355191

SCHEMBL16355191

COc1ccccc1-c1c(-c2ccccc2Cl)nc(-c2ccccc2Cl)n1C1(c2ccccc2Cl)N=C(c2ccccc2)C(c2ccccc2)=N1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 3/20 0.41
LMNA P02545 2/20 0.41
GAA P10253 1/20 0.41
PDE10A Q9Y233 3/20 0.37
PDE2A O00408 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PDE6D O43924 1/20 0.35
PDE6A P16499 1/20 0.35
PDE6G P18545 1/20 0.35
PDE4A P27815 1/20 0.35
PDE6B P35913 1/20 0.35
PDE6C P51160 1/20 0.35
PDE4B Q07343 1/20 0.35
PDE4C Q08493 1/20 0.35
PDE4D Q08499 1/20 0.35
PDE6H Q13956 1/20 0.35
MAPT P10636 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31734215 0.89 L3MBTL1 (0.43) ALDH1A1KDM4ESMN1; SMN2TSHRHSD17B10
SCHEMBL16355181 0.89 L3MBTL1 (0.43) ALDH1A1KDM4ESMN1; SMN2TSHRHSD17B10
SCHEMBL16355189 0.87 ALDH1A1 (0.40) ALDH1A1KDM4ELMNAGAAPDE10A
SCHEMBL8089682 0.87 L3MBTL1 (0.45) ALDH1A1KDM4EGAASMN1; SMN2TSHR
SCHEMBL16355184 0.86 PIK3CD (0.36) KDM4EPDE10APDE2AMAPTTP53
SCHEMBL26159617 0.85 ALDH1A1 (0.34) ALDH1A1KDM4ELMNASMN1; SMN2TSHR
SCHEMBL29895740 0.84 L3MBTL1 (0.43) ALDH1A1KDM4EPDE10ASMN1; SMN2TSHR
SCHEMBL16365751 0.84 L3MBTL1 (0.43) ALDH1A1KDM4EPDE10ASMN1; SMN2TSHR
SCHEMBL16355186 0.83 KDM4E (0.43) ALDH1A1KDM4ELMNAGAASMN1; SMN2
SCHEMBL16355187 0.83 KDM4E (0.43) ALDH1A1KDM4ELMNAGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140374677-A1 COLORED COMPOSITION, COLORED PHOTOSENSITIVE COMPOSITION, COLOR FILTER AND LIQUID CRYSTAL DISPLAY DEVICE EQUIPPED WITH SAME, ORGANIC EL DISPLAY DEVICE, AND SOLID-STATE IMAGE SENSOR FUJIFILM CORPORATION (JP) 2014-12-25 US disclosed
US-20140374677-A1 COLORED COMPOSITION, COLORED PHOTOSENSITIVE COMPOSITION, COLOR FILTER AND LIQUID CRYSTAL DISPLAY DEVICE EQUIPPED WITH SAME, ORGANIC EL DISPLAY DEVICE, AND SOLID-STATE IMAGE SENSOR FUJIFILM CORPORATION (JP) 2014-12-25 US disclosed